2cmp
From Proteopedia
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| - | [[Image:2cmp.png|left|200px]] | ||
| - | + | ==crystal structure of the DNA binding domain of G1P SMALL TERMINASE SUBUNIT from bacteriophage SF6== | |
| + | <StructureSection load='2cmp' size='340' side='right'caption='[[2cmp]], [[Resolution|resolution]] 1.58Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2cmp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_phage_SF6 Bacillus phage SF6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CMP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CMP FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.58Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cmp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cmp OCA], [https://pdbe.org/2cmp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cmp RCSB], [https://www.ebi.ac.uk/pdbsum/2cmp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cmp ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TERS_BPSF6 TERS_BPSF6] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cm/2cmp_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cmp ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | DNA packaging in tailed bacteriophages and in evolutionarily related herpesviruses is controlled by a viral-encoded terminase. As in a number of other phages, in the Bacillus subtilis bacteriophages SF6 and SPP1 the terminase complex consists of two proteins: G1P and G2P. The crystal structure of the N-terminal DNA-binding domain of the bacteriophage SF6 small terminase subunit G1P is reported. Structural comparison with other DNA-binding proteins allows a general model for the interaction of G1P with the packaging-initiation site to be proposed. | ||
| - | + | The 1.58 A resolution structure of the DNA-binding domain of bacteriophage SF6 small terminase provides new hints on DNA binding.,Benini S, Chechik M, Ortiz Lombardia M, Polier S, Leech A, Shevtsov MB, Alonso JC Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Apr 1;69(Pt 4):376-81., doi: 10.1107/S1744309113004399. Epub 2013 Mar 28. PMID:23545641<ref>PMID:23545641</ref> | |
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 2cmp" style="background-color:#fffaf0;"></div> | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Terminase 3D Structures|Terminase 3D Structures]] |
| - | [[Category: | + | == References == |
| - | [[Category: Alonso | + | <references/> |
| - | [[Category: Antson | + | __TOC__ |
| - | [[Category: Benini | + | </StructureSection> |
| - | [[Category: Chechik | + | [[Category: Bacillus phage SF6]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Ortiz-Lombardia | + | [[Category: Alonso JC]] |
| - | [[Category: Polier | + | [[Category: Antson AA]] |
| - | [[Category: Shevtsov | + | [[Category: Benini S]] |
| - | + | [[Category: Chechik M]] | |
| - | + | [[Category: DeLuchi D]] | |
| - | + | [[Category: Ortiz-Lombardia M]] | |
| - | + | [[Category: Polier S]] | |
| - | + | [[Category: Shevtsov MB]] | |
Current revision
crystal structure of the DNA binding domain of G1P SMALL TERMINASE SUBUNIT from bacteriophage SF6
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