2jvh
From Proteopedia
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| - | [[Image:2jvh.png|left|200px]] | ||
| - | + | ==Structure of C3-binding domain 4 of S. aureus protein Sbi== | |
| - | + | <StructureSection load='2jvh' size='340' side='right'caption='[[2jvh]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2jvh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JVH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JVH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jvh OCA], [https://pdbe.org/2jvh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jvh RCSB], [https://www.ebi.ac.uk/pdbsum/2jvh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jvh ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[2jvh]] is a 1 chain structure with sequence from [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/SBI_STAAM SBI_STAAM] Plays a role in the inhibition of both the innate and adaptive immune responses. Possesses two N-terminal domains that bind the Fc region of IgG and two domains that form a tripartite complex with complement factors C3b and CFH. By recruiting CFH and C3b, the secreted form acts as a potent complement inhibitor of the alternative pathway-mediated lysis.[UniProtKB:A6QJQ7]<ref>PMID:18550524</ref> | |
| - | == | + | == References == |
| - | < | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Staphylococcus aureus]] | [[Category: Staphylococcus aureus]] | ||
| - | [[Category: Bagby | + | [[Category: Bagby S]] |
| - | [[Category: Burman | + | [[Category: Burman J]] |
| - | [[Category: Clark | + | [[Category: Clark EA]] |
| - | + | [[Category: Upadhyay A]] | |
| - | [[Category: Upadhyay | + | [[Category: Van den Elsen JMH]] |
| - | [[Category: | + | |
| - | + | ||
Current revision
Structure of C3-binding domain 4 of S. aureus protein Sbi
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