2igp

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[[Image:2igp.png|left|200px]]
 
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{{STRUCTURE_2igp| PDB=2igp | SCENE= }}
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==Crystal Structure of Hec1 CH domain==
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<StructureSection load='2igp' size='340' side='right'caption='[[2igp]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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===Crystal Structure of Hec1 CH domain===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2igp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IGP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IGP FirstGlance]. <br>
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{{ABSTRACT_PUBMED_17195848}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2igp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2igp OCA], [https://pdbe.org/2igp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2igp RCSB], [https://www.ebi.ac.uk/pdbsum/2igp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2igp ProSAT]</span></td></tr>
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[[2igp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IGP OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/NDC80_HUMAN NDC80_HUMAN] Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.<ref>PMID:9315664</ref> <ref>PMID:12351790</ref> <ref>PMID:14654001</ref> <ref>PMID:15235793</ref> <ref>PMID:15062103</ref> <ref>PMID:15239953</ref> <ref>PMID:14699129</ref> <ref>PMID:15548592</ref> <ref>PMID:16732327</ref>
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<ref group="xtra">PMID:017195848</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ig/2igp_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2igp ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Harrison, S C.]]
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[[Category: Large Structures]]
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[[Category: Wei, R R.]]
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[[Category: Harrison SC]]
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[[Category: Alpha helice]]
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[[Category: Wei RR]]
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[[Category: Cell cycle]]
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Current revision

Crystal Structure of Hec1 CH domain

PDB ID 2igp

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