2krr

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2krr" [edit=sysop:move=sysop])
Current revision (09:51, 9 May 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2krr.png|left|200px]]
 
-
{{STRUCTURE_2krr| PDB=2krr | SCENE= }}
+
==Solution structure of the RBD1,2 domains from human nucleolin==
 +
<StructureSection load='2krr' size='340' side='right'caption='[[2krr]]' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[2krr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KRR FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2krr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2krr OCA], [https://pdbe.org/2krr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2krr RCSB], [https://www.ebi.ac.uk/pdbsum/2krr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2krr ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/NUCL_HUMAN NUCL_HUMAN] Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.<ref>PMID:10393184</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kr/2krr_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2krr ConSurf].
 +
<div style="clear:both"></div>
-
===Solution structure of the RBD1,2 domains from human nucleolin===
+
==See Also==
-
 
+
*[[Nucleolin|Nucleolin]]
-
 
+
== References ==
-
==About this Structure==
+
<references/>
-
[[2krr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRR OCA].
+
__TOC__
-
 
+
</StructureSection>
-
==Reference==
+
-
<ref group="xtra">PMID:020376532</ref><references group="xtra"/>
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Arumugam, N.]]
+
[[Category: Large Structures]]
-
[[Category: Bates, P J.]]
+
[[Category: Arumugam N]]
-
[[Category: Lane, A N.]]
+
[[Category: Bates PJ]]
-
[[Category: Maliekal, J.]]
+
[[Category: Lane AN]]
-
[[Category: Miller, C.]]
+
[[Category: Maliekal J]]
-
[[Category: Trent, J O.]]
+
[[Category: Miller C]]
-
[[Category: Dna-binding]]
+
[[Category: Trent JO]]
-
[[Category: Methylation]]
+
-
[[Category: Nuclear protein]]
+
-
[[Category: Nucleus]]
+
-
[[Category: Phosphoprotein]]
+
-
[[Category: Rna-binding]]
+

Current revision

Solution structure of the RBD1,2 domains from human nucleolin

PDB ID 2krr

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2krr"
Personal tools