2pbr
From Proteopedia
(Difference between revisions)
m (Protected "2pbr" [edit=sysop:move=sysop]) |
|||
| (7 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2pbr.png|left|200px]] | ||
| - | + | ==Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5== | |
| + | <StructureSection load='2pbr' size='340' side='right'caption='[[2pbr]], [[Resolution|resolution]] 1.96Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2pbr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PBR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PBR FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.96Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pbr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pbr OCA], [https://pdbe.org/2pbr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pbr RCSB], [https://www.ebi.ac.uk/pdbsum/2pbr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pbr ProSAT], [https://www.topsan.org/Proteins/RSGI/2pbr TOPSAN]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/KTHY_AQUAE KTHY_AQUAE] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pb/2pbr_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pbr ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Thymidylate kinase 3D structures|Thymidylate kinase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | [[ | + | [[Category: Aquifex aeolicus VF5]] |
| - | [[Category: Aquifex aeolicus]] | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Ebihara A]] |
| - | [[Category: Ebihara | + | [[Category: Jeyakanthan J]] |
| - | [[Category: Jeyakanthan | + | [[Category: Kanaujia SP]] |
| - | [[Category: Kanaujia | + | [[Category: Kuramitsu S]] |
| - | [[Category: Kuramitsu | + | [[Category: Nakagawa N]] |
| - | [[Category: Nakagawa | + | [[Category: Sekar K]] |
| - | + | [[Category: Shinkai A]] | |
| - | + | [[Category: Shiro Y]] | |
| - | [[Category: Sekar | + | [[Category: Vasuki Ranjani C]] |
| - | [[Category: Shinkai | + | [[Category: Yokoyama S]] |
| - | [[Category: Shiro | + | |
| - | [[Category: | + | |
| - | [[Category: | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5
| |||||||||||
