2j0x

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[[Image:2j0x.png|left|200px]]
 
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{{STRUCTURE_2j0x| PDB=2j0x | SCENE= }}
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==CRYSTAL STRUCTURE OF E. COLI ASPARTOKINASE III IN COMPLEX WITH LYSINE AND ASPARTATE (T-STATE)==
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<StructureSection load='2j0x' size='340' side='right'caption='[[2j0x]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF E. COLI ASPARTOKINASE III IN COMPLEX WITH LYSINE AND ASPARTATE (T-STATE)===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2j0x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J0X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J0X FirstGlance]. <br>
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{{ABSTRACT_PUBMED_16905770}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ASP:ASPARTIC+ACID'>ASP</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j0x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j0x OCA], [https://pdbe.org/2j0x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j0x RCSB], [https://www.ebi.ac.uk/pdbsum/2j0x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j0x ProSAT]</span></td></tr>
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[[2j0x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J0X OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/AK3_ECOLI AK3_ECOLI]
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<ref group="xtra">PMID:016905770</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Category: Aspartate kinase]]
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j0/2j0x_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2j0x ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Hawkins, A R.]]
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[[Category: Large Structures]]
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[[Category: Kotaka, M.]]
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[[Category: Hawkins AR]]
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[[Category: Lockyer, M.]]
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[[Category: Kotaka M]]
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[[Category: Ren, J.]]
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[[Category: Lockyer M]]
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[[Category: Stammers, D K.]]
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[[Category: Ren J]]
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[[Category: Act domain]]
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[[Category: Stammers DK]]
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[[Category: Allosteric regulation]]
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[[Category: Amino acid biosynthesis]]
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[[Category: Amino-acid biosynthesis]]
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[[Category: Aspartate pathway]]
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[[Category: Aspartokinase]]
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[[Category: Feedback inhibition]]
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[[Category: Kinase]]
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[[Category: Lysine]]
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[[Category: Lysine biosynthesis]]
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[[Category: Transferase]]
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Current revision

CRYSTAL STRUCTURE OF E. COLI ASPARTOKINASE III IN COMPLEX WITH LYSINE AND ASPARTATE (T-STATE)

PDB ID 2j0x

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