1vs1

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[[Image:1vs1.gif|left|200px]]<br /><applet load="1vs1" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1vs1, resolution 2.30&Aring;" />
 
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'''Crystal structure of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase) from Aeropyrum pernix in complex with Mn2+ and PEP'''<br />
 
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==About this Structure==
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==Crystal structure of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase) from Aeropyrum pernix in complex with Mn2+ and PEP==
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1VS1 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix] with <scene name='pdbligand=MN:'>MN</scene> and <scene name='pdbligand=PEP:'>PEP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/3-deoxy-7-phosphoheptulonate_synthase 3-deoxy-7-phosphoheptulonate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.54 2.5.1.54] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VS1 OCA].
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<StructureSection load='1vs1' size='340' side='right'caption='[[1vs1]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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[[Category: 3-deoxy-7-phosphoheptulonate synthase]]
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== Structural highlights ==
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[[Category: Aeropyrum pernix]]
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<table><tr><td colspan='2'>[[1vs1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VS1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VS1 FirstGlance]. <br>
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[[Category: Single protein]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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[[Category: Bauerle, R.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PEP:PHOSPHOENOLPYRUVATE'>PEP</scene></td></tr>
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[[Category: Kretsinger, R H.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vs1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vs1 OCA], [https://pdbe.org/1vs1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vs1 RCSB], [https://www.ebi.ac.uk/pdbsum/1vs1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vs1 ProSAT]</span></td></tr>
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[[Category: Shumilin, I A.]]
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</table>
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[[Category: Woodard, R W.]]
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== Function ==
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[[Category: Wu, J.]]
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[https://www.uniprot.org/uniprot/Q9YEJ7_AERPE Q9YEJ7_AERPE]
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[[Category: Zhou, L.]]
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== Evolutionary Conservation ==
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[[Category: MN]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: PEP]]
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Check<jmol>
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[[Category: (beta/alpha)8 barrel]]
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vs/1vs1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vs1 ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:38:01 2008''
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==See Also==
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*[[DAHP synthase 3D structures|DAHP synthase 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Aeropyrum pernix]]
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[[Category: Large Structures]]
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[[Category: Bauerle R]]
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[[Category: Kretsinger RH]]
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[[Category: Shumilin IA]]
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[[Category: Woodard RW]]
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[[Category: Wu J]]
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[[Category: Zhou L]]

Current revision

Crystal structure of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase) from Aeropyrum pernix in complex with Mn2+ and PEP

PDB ID 1vs1

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