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2o4x
From Proteopedia
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| - | [[Image:2o4x.png|left|200px]] | ||
| - | + | ==Crystal structure of human P100 tudor domain== | |
| - | + | <StructureSection load='2o4x' size='340' side='right'caption='[[2o4x]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2o4x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O4X FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o4x OCA], [https://pdbe.org/2o4x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o4x RCSB], [https://www.ebi.ac.uk/pdbsum/2o4x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o4x ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[2o4x]] is a 2 chain structure with sequence from [ | + | == Function == |
| + | [https://www.uniprot.org/uniprot/SND1_HUMAN SND1_HUMAN] Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).<ref>PMID:7651391</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o4/2o4x_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2o4x ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Cheng | + | [[Category: Large Structures]] |
| - | [[Category: Liu | + | [[Category: Cheng C]] |
| - | [[Category: Rao | + | [[Category: Liu ZJ]] |
| - | [[Category: Shaw | + | [[Category: Rao Z]] |
| - | [[Category: Silvennoinen | + | [[Category: Shaw N]] |
| - | [[Category: Wang | + | [[Category: Silvennoinen O]] |
| - | [[Category: Xu | + | [[Category: Wang BC]] |
| - | [[Category: Yang | + | [[Category: Xu H]] |
| - | [[Category: Zhao | + | [[Category: Yang J]] |
| - | + | [[Category: Zhao M]] | |
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| - | + | ||
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Current revision
Crystal structure of human P100 tudor domain
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Categories: Homo sapiens | Large Structures | Cheng C | Liu ZJ | Rao Z | Shaw N | Silvennoinen O | Wang BC | Xu H | Yang J | Zhao M
