2juf

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2juf" [edit=sysop:move=sysop])
Current revision (19:05, 29 May 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2juf.png|left|200px]]
 
-
{{STRUCTURE_2juf| PDB=2juf | SCENE= }}
+
==NMR solution structure of PARC CPH Domain. NESG Target HR3443B/SGC-Toronto==
-
 
+
<StructureSection load='2juf' size='340' side='right'caption='[[2juf]]' scene=''>
-
===NMR solution structure of PARC CPH Domain. NESG Target HR3443B/SGC-Toronto===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[2juf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JUF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JUF FirstGlance]. <br>
-
 
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2juf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2juf OCA], [https://pdbe.org/2juf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2juf RCSB], [https://www.ebi.ac.uk/pdbsum/2juf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2juf ProSAT], [https://www.topsan.org/Proteins/NESGC/2juf TOPSAN]</span></td></tr>
-
[[2juf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JUF OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CUL9_HUMAN CUL9_HUMAN] Core component of a Cul9-RING ubiquitin-protein ligase complex, a complex that mediates ubiquitination and subsequent degradation of BIRC5 and is required to maintain microtubule dynamics and genome integrity. Acts downstream of the 3M complex, which inhibits CUL9 activity, leading to prevent ubiquitination of BIRC5 (PubMed:24793696). Cytoplasmic anchor protein in p53/TP53-associated protein complex. Regulates the subcellular localization of p53/TP53 and subsequent function (PubMed:12526791, PubMed:17332328).<ref>PMID:12526791</ref> <ref>PMID:17332328</ref> <ref>PMID:24793696</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ju/2juf_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2juf ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Large Structures]]
-
[[Category: Dhe-Paganon, S.]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Duan, S.]]
+
[[Category: Dhe-Paganon S]]
-
[[Category: Edwards, A M.]]
+
[[Category: Duan S]]
-
[[Category: Karra, M.]]
+
[[Category: Edwards AM]]
-
[[Category: Kaustov, L.]]
+
[[Category: Karra M]]
-
[[Category: Lemak, S.]]
+
[[Category: Kaustov L]]
-
[[Category: Liao, J C.C.]]
+
[[Category: Lemak S]]
-
[[Category: Muhandiram, R.]]
+
[[Category: Liao JCC]]
-
[[Category: NESG, Northeast Structural Genomics Consortium.]]
+
[[Category: Muhandiram R]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Srisailam SH]]
-
[[Category: Srisailam, S H.]]
+
[[Category: Sundstrom M]]
-
[[Category: Sundstrom, M.]]
+
[[Category: Weigelt J]]
-
[[Category: Weigelt, J.]]
+
-
[[Category: Atp-binding]]
+
-
[[Category: Cph domain]]
+
-
[[Category: Gene regulation]]
+
-
[[Category: Metal-binding]]
+
-
[[Category: Nesg]]
+
-
[[Category: Northeast structural genomics consortium]]
+
-
[[Category: Nucleotide-binding]]
+
-
[[Category: Protein structure initiative]]
+
-
[[Category: Psi-2]]
+
-
[[Category: Sgc]]
+
-
[[Category: Structural genomics consortium]]
+
-
[[Category: Ubl conjugation pathway]]
+
-
[[Category: Zinc-finger]]
+

Current revision

NMR solution structure of PARC CPH Domain. NESG Target HR3443B/SGC-Toronto

PDB ID 2juf

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2juf"
Personal tools