2hdd
From Proteopedia
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| - | [[Image:2hdd.png|left|200px]] | ||
| - | + | ==ENGRAILED HOMEODOMAIN Q50K VARIANT DNA COMPLEX== | |
| - | + | <StructureSection load='2hdd' size='340' side='right'caption='[[2hdd]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2hdd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HDD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HDD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hdd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hdd OCA], [https://pdbe.org/2hdd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hdd RCSB], [https://www.ebi.ac.uk/pdbsum/2hdd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hdd ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[2hdd]] is a 4 chain structure with sequence from [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/HMEN_DROME HMEN_DROME] This protein specifies the body segmentation pattern. It is required for the development of the central nervous system. Transcriptional regulator that represses activated promoters. Wg signaling operates by inactivating the SGG repression of EN autoactivation. | |
| - | == | + | == Evolutionary Conservation == |
| - | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hd/2hdd_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hdd ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Drosophila melanogaster]] | [[Category: Drosophila melanogaster]] | ||
| - | [[Category: Ades | + | [[Category: Large Structures]] |
| - | [[Category: Chambers | + | [[Category: Ades SE]] |
| - | [[Category: Pabo | + | [[Category: Chambers KA]] |
| - | [[Category: Rould | + | [[Category: Pabo CO]] |
| - | [[Category: Sauer | + | [[Category: Rould MA]] |
| - | [[Category: Tucker-Kellogg | + | [[Category: Sauer RT]] |
| - | + | [[Category: Tucker-Kellogg L]] | |
| - | + | ||
Current revision
ENGRAILED HOMEODOMAIN Q50K VARIANT DNA COMPLEX
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