This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2or2

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:05, 21 February 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2or2.png|left|200px]]
 
-
{{STRUCTURE_2or2| PDB=2or2 | SCENE= }}
+
==Structure of the W47A/W242A Mutant of Bacterial Phosphatidylinositol-Specific Phospholipase C==
 +
<StructureSection load='2or2' size='340' side='right'caption='[[2or2]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[2or2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thuringiensis Bacillus thuringiensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OR2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OR2 FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.84&#8491;</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2or2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2or2 OCA], [https://pdbe.org/2or2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2or2 RCSB], [https://www.ebi.ac.uk/pdbsum/2or2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2or2 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/PLC_BACTU PLC_BACTU] Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/or/2or2_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2or2 ConSurf].
 +
<div style="clear:both"></div>
-
===Structure of the W47A/W242A Mutant of Bacterial Phosphatidylinositol-Specific Phospholipase C===
+
==See Also==
-
 
+
*[[Phospholipase C|Phospholipase C]]
-
{{ABSTRACT_PUBMED_17213187}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
-
[[2or2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_thuringiensis Bacillus thuringiensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OR2 OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:017213187</ref><references group="xtra"/>
+
[[Category: Bacillus thuringiensis]]
[[Category: Bacillus thuringiensis]]
-
[[Category: Phosphatidylinositol diacylglycerol-lyase]]
+
[[Category: Large Structures]]
-
[[Category: Head, J F.]]
+
[[Category: Head JF]]
-
[[Category: Roberts, M F.]]
+
[[Category: Roberts MF]]
-
[[Category: Seaton, B A.]]
+
[[Category: Seaton BA]]
-
[[Category: Shao, C.]]
+
[[Category: Shao C]]
-
[[Category: Shi, X.]]
+
[[Category: Shi X]]
-
[[Category: Wehbi, H.]]
+
[[Category: Wehbi H]]
-
[[Category: Zambonelli, C.]]
+
[[Category: Zambonelli C]]
-
[[Category: Dimer]]
+
-
[[Category: Interfacially impaired]]
+
-
[[Category: Lyase]]
+
-
[[Category: Membrane binding]]
+
-
[[Category: Phosphatidylinositol-specific phospholipase c]]
+
-
[[Category: Pi-plc]]
+
-
[[Category: Tim barrel]]
+

Current revision

Structure of the W47A/W242A Mutant of Bacterial Phosphatidylinositol-Specific Phospholipase C

PDB ID 2or2

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools