2fem
From Proteopedia
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| - | [[Image:2fem.png|left|200px]] | ||
| - | + | ==Mutant R188M of the Cytidine Monophosphate Kinase From E. Coli== | |
| + | <StructureSection load='2fem' size='340' side='right'caption='[[2fem]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2fem]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FEM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FEM FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fem OCA], [https://pdbe.org/2fem PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fem RCSB], [https://www.ebi.ac.uk/pdbsum/2fem PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fem ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/KCY_ECOLI KCY_ECOLI] ATP, dATP, and GTP are equally effective as phosphate donors. CMP and dCMP are the best phosphate acceptors.<ref>PMID:8190075</ref> <ref>PMID:7836281</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fe/2fem_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fem ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Cytidine monophosphate kinase|Cytidine monophosphate kinase]] | |
| - | + | == References == | |
| - | + | <references/> | |
| - | + | __TOC__ | |
| - | [[ | + | </StructureSection> |
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[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Alexov | + | [[Category: Large Structures]] |
| - | [[Category: Barzu | + | [[Category: Alexov E]] |
| - | [[Category: Bertrand | + | [[Category: Barzu O]] |
| - | [[Category: Briozzo | + | [[Category: Bertrand T]] |
| - | [[Category: Bucurenci | + | [[Category: Briozzo P]] |
| - | [[Category: Gilles | + | [[Category: Bucurenci N]] |
| - | [[Category: Munier-Lehmann | + | [[Category: Gilles AM]] |
| - | [[Category: Ofiteru | + | [[Category: Munier-Lehmann H]] |
| - | [[Category: Tourneux | + | [[Category: Ofiteru A]] |
| - | + | [[Category: Tourneux L]] | |
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Current revision
Mutant R188M of the Cytidine Monophosphate Kinase From E. Coli
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