This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2gse

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:29, 14 February 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2gse.png|left|200px]]
 
-
{{STRUCTURE_2gse| PDB=2gse | SCENE= }}
+
==Crystal Structure of Human Dihydropyrimidinease-like 2==
-
 
+
<StructureSection load='2gse' size='340' side='right'caption='[[2gse]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-
===Crystal Structure of Human Dihydropyrimidinease-like 2===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[2gse]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GSE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GSE FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_17250651}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gse FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gse OCA], [https://pdbe.org/2gse PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gse RCSB], [https://www.ebi.ac.uk/pdbsum/2gse PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gse ProSAT]</span></td></tr>
-
[[2gse]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GSE OCA].
+
</table>
-
 
+
== Function ==
-
==Reference==
+
[https://www.uniprot.org/uniprot/DPYL2_HUMAN DPYL2_HUMAN] Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton (By similarity). Plays a role in neuron projection morphogenesis.<ref>PMID:11477421</ref> <ref>PMID:15466863</ref>
-
<ref group="xtra">PMID:017250651</ref><references group="xtra"/>
+
== Evolutionary Conservation ==
-
[[Category: Dihydropyrimidinase]]
+
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gs/2gse_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gse ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Arrowsmith, C.]]
+
[[Category: Large Structures]]
-
[[Category: Berg, S Van Den.]]
+
[[Category: Arrowsmith C]]
-
[[Category: Berglund, H.]]
+
[[Category: Berglund H]]
-
[[Category: Collins, R.]]
+
[[Category: Collins R]]
-
[[Category: Edwards, A.]]
+
[[Category: Edwards A]]
-
[[Category: Ehn, M.]]
+
[[Category: Ehn M]]
-
[[Category: Flodin, S.]]
+
[[Category: Flodin S]]
-
[[Category: Flores, A.]]
+
[[Category: Flores A]]
-
[[Category: Graslund, S.]]
+
[[Category: Graslund S]]
-
[[Category: Hallberg, B M.]]
+
[[Category: Hallberg BM]]
-
[[Category: Hammarstrom, M.]]
+
[[Category: Hammarstrom M]]
-
[[Category: Holmberg-Schiavone, L.]]
+
[[Category: Holmberg-Schiavone L]]
-
[[Category: Kotenyova, T.]]
+
[[Category: Kotenyova T]]
-
[[Category: Kursula, P.]]
+
[[Category: Kursula P]]
-
[[Category: Nilsson-Ehle, P.]]
+
[[Category: Nilsson-Ehle P]]
-
[[Category: Nordlund, P.]]
+
[[Category: Nordlund P]]
-
[[Category: Nyman, T.]]
+
[[Category: Nyman T]]
-
[[Category: Ogg, D.]]
+
[[Category: Ogg D]]
-
[[Category: Persson, C.]]
+
[[Category: Persson C]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Sagemark J]]
-
[[Category: Sagemark, J.]]
+
[[Category: Stenmark P]]
-
[[Category: Stenmark, P.]]
+
[[Category: Sundstrom M]]
-
[[Category: Sundstrom, M.]]
+
[[Category: Thorsell AG]]
-
[[Category: Thorsell, A G]]
+
[[Category: Uppenberg J]]
-
[[Category: Uppenberg, J.]]
+
[[Category: Van Den Berg S]]
-
[[Category: Weigelt, J.]]
+
[[Category: Weigelt J]]
-
[[Category: Alpha/beta barrel]]
+
-
[[Category: Collapsin response mediator protein 2]]
+
-
[[Category: Crmp2]]
+
-
[[Category: Dihydropyrimidinase-related protein 2]]
+
-
[[Category: Drp2]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Sgc]]
+
-
[[Category: Structural genomic]]
+
-
[[Category: Structural genomics consortium]]
+

Current revision

Crystal Structure of Human Dihydropyrimidinease-like 2

PDB ID 2gse

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2gse"
Personal tools