2kl7
From Proteopedia
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| - | [[Image:2kl7.png|left|200px]] | ||
| - | + | ==Solution NMR Structure of the EGF-like 1 Domain of Human Fibulin-4. Northeast Structural Genomics Target HR6275== | |
| - | + | <StructureSection load='2kl7' size='340' side='right'caption='[[2kl7]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2kl7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KL7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KL7 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kl7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kl7 OCA], [https://pdbe.org/2kl7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kl7 RCSB], [https://www.ebi.ac.uk/pdbsum/2kl7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kl7 ProSAT], [https://www.topsan.org/Proteins/NESGC/2kl7 TOPSAN]</span></td></tr> |
| - | [[2kl7]] is a 1 chain structure with sequence from [ | + | </table> |
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/FBLN4_HUMAN FBLN4_HUMAN] Autosomal recessive cutis laxa type 1;Lethal arteriopathy syndrome due to Fibulin-4 deficiency. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:16685658</ref> <ref>PMID:17937443</ref> <ref>PMID:19664000</ref> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FBLN4_HUMAN FBLN4_HUMAN] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kl/2kl7_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kl7 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Anderson S]] |
| - | [[Category: | + | [[Category: Chiang Y]] |
| - | [[Category: | + | [[Category: Montelione GT]] |
| - | [[Category: Rossi | + | [[Category: Rossi P]] |
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Current revision
Solution NMR Structure of the EGF-like 1 Domain of Human Fibulin-4. Northeast Structural Genomics Target HR6275
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