2kro
From Proteopedia
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| - | [[Image:2kro.png|left|200px]] | ||
| - | + | ==RDC refined high resolution structure of the third SH3 domain of CD2AP== | |
| + | <StructureSection load='2kro' size='340' side='right'caption='[[2kro]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2kro]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KRO FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kro FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kro OCA], [https://pdbe.org/2kro PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kro RCSB], [https://www.ebi.ac.uk/pdbsum/2kro PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kro ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CD2AP_MOUSE CD2AP_MOUSE] Required for cytokinesis (By similarity). Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus.<ref>PMID:10514378</ref> | ||
| - | == | + | ==See Also== |
| - | + | *[[CD2-associated protein 3D structures|CD2-associated protein 3D structures]] | |
| - | + | == References == | |
| - | == | + | <references/> |
| - | [[ | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Azuaga | + | [[Category: Azuaga AI]] |
| - | [[Category: Blackledge | + | [[Category: Blackledge M]] |
| - | + | [[Category: Ortega Roldan J]] | |
| - | [[Category: Roldan | + | [[Category: Van Nuland NAJ]] |
| - | [[Category: | + | |
| - | + | ||
| - | + | ||
Current revision
RDC refined high resolution structure of the third SH3 domain of CD2AP
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