2io7
From Proteopedia
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- | [[Image:2io7.png|left|200px]] | ||
- | + | ==E. coli Bifunctional glutathionylspermidine synthetase/amidase Incomplex with Mg2+ and AMPPNP== | |
- | + | <StructureSection load='2io7' size='340' side='right'caption='[[2io7]], [[Resolution|resolution]] 2.70Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2io7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IO7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IO7 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
- | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2io7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2io7 OCA], [https://pdbe.org/2io7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2io7 RCSB], [https://www.ebi.ac.uk/pdbsum/2io7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2io7 ProSAT]</span></td></tr> |
- | [[2io7]] is a 2 chain structure with sequence from [ | + | </table> |
- | + | == Function == | |
- | == | + | [https://www.uniprot.org/uniprot/GSP_ECOLI GSP_ECOLI] Catalyzes the formation of an amide bond between glutathione and spermidine coupled with hydrolysis of ATP; also catalyzes the hydrolysis of glutathionylspermidine to glutathione and spermidine. |
- | < | + | == Evolutionary Conservation == |
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/io/2io7_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2io7 ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
- | [[Category: Chiang | + | [[Category: Large Structures]] |
- | [[Category: Chong | + | [[Category: Chiang BY]] |
- | [[Category: Coward | + | [[Category: Chong CM]] |
- | [[Category: Ko | + | [[Category: Coward JK]] |
- | [[Category: Lin | + | [[Category: Ko TP]] |
- | [[Category: Pai | + | [[Category: Lin CH]] |
- | [[Category: Wang | + | [[Category: Pai CH]] |
- | [[Category: Yen | + | [[Category: Wang AH-J]] |
- | + | [[Category: Yen FJ]] | |
- | + | ||
- | + |
Current revision
E. coli Bifunctional glutathionylspermidine synthetase/amidase Incomplex with Mg2+ and AMPPNP
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Categories: Escherichia coli | Large Structures | Chiang BY | Chong CM | Coward JK | Ko TP | Lin CH | Pai CH | Wang AH-J | Yen FJ