2k06

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[[Image:2k06.png|left|200px]]
 
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{{STRUCTURE_2k06| PDB=2k06 | SCENE= }}
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==Solution structure of the aminoterminal domain of E. coli NusG==
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<StructureSection load='2k06' size='340' side='right'caption='[[2k06]]' scene=''>
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===Solution structure of the aminoterminal domain of E. coli NusG===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2k06]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K06 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_019500594}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k06 OCA], [https://pdbe.org/2k06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k06 RCSB], [https://www.ebi.ac.uk/pdbsum/2k06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k06 ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[2k06]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K06 OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/NUSG_ECOLI NUSG_ECOLI] Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA and phage lambda N-mediated transcriptional antitermination.<ref>PMID:1532577</ref> <ref>PMID:1547498</ref> <ref>PMID:7505669</ref> <ref>PMID:8422985</ref> <ref>PMID:7868616</ref> <ref>PMID:7761393</ref> <ref>PMID:10383769</ref> <ref>PMID:10820031</ref> <ref>PMID:14973028</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k0/2k06_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k06 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Roesch, P.]]
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[[Category: Large Structures]]
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[[Category: Scheckenhofer, U.]]
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[[Category: Roesch P]]
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[[Category: Schweimer, K.]]
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[[Category: Scheckenhofer U]]
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[[Category: Nusg]]
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[[Category: Schweimer K]]
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[[Category: Transcription]]
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[[Category: Transcription antitermination]]
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[[Category: Transcription regulation]]
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[[Category: Transcription termination]]
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Current revision

Solution structure of the aminoterminal domain of E. coli NusG

PDB ID 2k06

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