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2p3v

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[[Image:2p3v.png|left|200px]]
 
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{{STRUCTURE_2p3v| PDB=2p3v | SCENE= }}
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==Thermotoga maritima IMPase TM1415==
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<StructureSection load='2p3v' size='340' side='right'caption='[[2p3v]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2p3v]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P3V FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SRT:S,R+MESO-TARTARIC+ACID'>SRT</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p3v OCA], [https://pdbe.org/2p3v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p3v RCSB], [https://www.ebi.ac.uk/pdbsum/2p3v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p3v ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BSUHB_THEMA BSUHB_THEMA] Phosphatase with broad specificity; it can dephosphorylate fructose 1,6-bisphosphate, both D and L isomers of inositol-1-phosphate (I-1-P) but displaying a 20-fold higher rate of hydrolysis of D-I-1-P than of the L isomer, 2'-AMP, pNPP, inositol-2-phosphate, beta-glycerol phosphate, and alpha-D-glucose-1-phosphate. Cannot hydrolyze glucose-6-phosphate, fructose-6-phosphate, 5'-AMP and NAD(+). May be involved in the biosynthesis of a unique osmolyte, di-myo-inositol 1,1-phosphate.<ref>PMID:10508089</ref> <ref>PMID:11062561</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p3/2p3v_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p3v ConSurf].
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<div style="clear:both"></div>
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===Thermotoga maritima IMPase TM1415===
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==See Also==
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*[[Inositol monophosphatase 3D structures|Inositol monophosphatase 3D structures]]
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{{ABSTRACT_PUBMED_17419729}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[2p3v]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3V OCA].
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</StructureSection>
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[[Category: Large Structures]]
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==Reference==
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[[Category: Thermotoga maritima MSB8]]
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<ref group="xtra">PMID:017419729</ref><references group="xtra"/>
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[[Category: Li W]]
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[[Category: Inositol-phosphate phosphatase]]
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[[Category: Roberts MF]]
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[[Category: Thermotoga maritima]]
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[[Category: Stec B]]
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[[Category: Li, W.]]
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[[Category: Stieglitz KA]]
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[[Category: Roberts, M F.]]
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[[Category: Stec, B.]]
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[[Category: Stieglitz, K A.]]
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[[Category: Asymmetric tetramer]]
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[[Category: Hydrolase]]
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[[Category: Inositol]]
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[[Category: Phosphatase]]
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Current revision

Thermotoga maritima IMPase TM1415

PDB ID 2p3v

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