2pr0
From Proteopedia
(Difference between revisions)
m (Protected "2pr0" [edit=sysop:move=sysop]) |
|||
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2pr0.png|left|200px]] | ||
| - | + | ==Crystal structure of Sylvaticin, a new secreted protein from Pythium Sylvaticum== | |
| + | <StructureSection load='2pr0' size='340' side='right'caption='[[2pr0]], [[Resolution|resolution]] 1.72Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2pr0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pythium_sylvaticum Pythium sylvaticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PR0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PR0 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2pos|2pos]]</div></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pr0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pr0 OCA], [https://pdbe.org/2pr0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pr0 RCSB], [https://www.ebi.ac.uk/pdbsum/2pr0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pr0 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pr/2pr0_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pr0 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The structure of sylvaticin, a 10 kDa major pythin protein excreted by the parasitic oomycete Pythium sylvaticum, has been determined. Although closely related to alpha-elicitins in its biological response, toxicity and overall structure, sylvaticin presents a number of structural features that make it an unusual member of the elicitin class. Elicitins possess a large hydrophobic cavity and the mechanism of the systemic acquired resistance induced in planta is known to proceed through lipid transport and complexation within this cavity. Unlike other elicitins, sylvaticin contains tryptophan residues, one of which points inwards towards the central cavity, thus limiting access to sterols. In the case of sylvaticin, the sterol-transport mechanism is likely to be of less importance compared with other members of the elicitin family and still remains to be fully characterized. | ||
| - | + | Structure of sylvaticin, a new alpha-elicitin-like protein from Pythium sylvaticum.,Lascombe MB, Retailleau P, Ponchet M, Industri B, Blein JP, Prange T Acta Crystallogr D Biol Crystallogr. 2007 Oct;63(Pt 10):1102-8. Epub 2007, Sep 19. PMID:17881828<ref>PMID:17881828</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | <div class="pdbe-citations 2pr0" style="background-color:#fffaf0;"></div> | |
| - | + | == References == | |
| - | + | <references/> | |
| - | == | + | __TOC__ |
| - | < | + | </StructureSection> |
| + | [[Category: Large Structures]] | ||
[[Category: Pythium sylvaticum]] | [[Category: Pythium sylvaticum]] | ||
| - | [[Category: Lascombe, M B | + | [[Category: Lascombe, M B]] |
| - | [[Category: Prange, T | + | [[Category: Prange, T]] |
| - | [[Category: Retailleau, P | + | [[Category: Retailleau, P]] |
[[Category: Elicitin]] | [[Category: Elicitin]] | ||
[[Category: Toxin]] | [[Category: Toxin]] | ||
Current revision
Crystal structure of Sylvaticin, a new secreted protein from Pythium Sylvaticum
| |||||||||||
