2fj2

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[[Image:2fj2.png|left|200px]]
 
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{{STRUCTURE_2fj2| PDB=2fj2 | SCENE= }}
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==Crystal Structure of Viral Macrophage Inflammatory Protein-II==
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<StructureSection load='2fj2' size='340' side='right'caption='[[2fj2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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===Crystal Structure of Viral Macrophage Inflammatory Protein-II===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2fj2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_herpesvirus_8_strain_GK18 Human herpesvirus 8 strain GK18]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FJ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FJ2 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fj2 OCA], [https://pdbe.org/2fj2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fj2 RCSB], [https://www.ebi.ac.uk/pdbsum/2fj2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fj2 ProSAT]</span></td></tr>
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[[2fj2]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FJ2 OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/VMI2_HHV8P VMI2_HHV8P] Blocks infection by several different human immunodeficiency virus type 1 (HIV-1) strains. This occurs because vMIP-II binds to a wide range of chemokine receptors. May form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions.
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<ref group="xtra">PMID:017243149</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Category: Cao, R.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Dong, C Z.]]
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Check<jmol>
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[[Category: Gao, Y G.]]
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<jmolCheckbox>
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[[Category: Huang, Z.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fj/2fj2_consurf.spt"</scriptWhenChecked>
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[[Category: Kumar, S.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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[[Category: Li, Y.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Liu, D.]]
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</jmolCheckbox>
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[[Category: Wilson, S R.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fj2 ConSurf].
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[[Category: Anti-hiv]]
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<div style="clear:both"></div>
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[[Category: Chemokine]]
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__TOC__
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[[Category: Herpesvirus]]
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</StructureSection>
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[[Category: Human herpesvirus 8 strain GK18]]
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[[Category: Large Structures]]
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[[Category: Cao R]]
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[[Category: Dong CZ]]
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[[Category: Gao YG]]
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[[Category: Huang Z]]
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[[Category: Kumar S]]
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[[Category: Li Y]]
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[[Category: Liu D]]
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[[Category: Wilson SR]]

Current revision

Crystal Structure of Viral Macrophage Inflammatory Protein-II

PDB ID 2fj2

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