2hqc
From Proteopedia
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| - | [[Image:2hqc.png|left|200px]] | ||
| - | + | ==Conformation of the AcrB Multidrug Efflux Pump in Mutants of the Putative Proton Relay Pathway== | |
| - | + | <StructureSection load='2hqc' size='340' side='right'caption='[[2hqc]], [[Resolution|resolution]] 3.56Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2hqc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HQC FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.56Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hqc OCA], [https://pdbe.org/2hqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hqc RCSB], [https://www.ebi.ac.uk/pdbsum/2hqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hqc ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[2hqc]] is a 1 chain structure with sequence from [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref> | |
| - | == | + | == Evolutionary Conservation == |
| - | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [[Category: Escherichia coli | + | Check<jmol> |
| - | [[Category: Gu | + | <jmolCheckbox> |
| - | [[Category: Li | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hq/2hqc_consurf.spt"</scriptWhenChecked> |
| - | [[Category: McDermott | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [[Category: Nikaido | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [[Category: Su | + | </jmolCheckbox> |
| - | [[Category: Takatsuka | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hqc ConSurf]. |
| - | [[Category: Yu | + | <div style="clear:both"></div> |
| - | + | == References == | |
| - | + | <references/> | |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Gu R]] | ||
| + | [[Category: Li M]] | ||
| + | [[Category: McDermott G]] | ||
| + | [[Category: Nikaido H]] | ||
| + | [[Category: Su C-C]] | ||
| + | [[Category: Takatsuka Y]] | ||
| + | [[Category: Yu EW]] | ||
Current revision
Conformation of the AcrB Multidrug Efflux Pump in Mutants of the Putative Proton Relay Pathway
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Categories: Escherichia coli K-12 | Large Structures | Gu R | Li M | McDermott G | Nikaido H | Su C-C | Takatsuka Y | Yu EW
