1wi0

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[[Image:1wi0.jpg|left|200px]]<br /><applet load="1wi0" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1wi0" />
 
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'''Solution structure of the PB1 domain of mouse mitogen activated protein kinase kinase 5 (MAP2K5)'''<br />
 
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==About this Structure==
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==Solution structure of the PB1 domain of mouse mitogen activated protein kinase kinase 5 (MAP2K5)==
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1WI0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WI0 OCA].
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<StructureSection load='1wi0' size='340' side='right'caption='[[1wi0]]' scene=''>
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[[Category: Mus musculus]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[1wi0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WI0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WI0 FirstGlance]. <br>
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[[Category: Hayashi, F.]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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[[Category: Inoue, M.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wi0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wi0 OCA], [https://pdbe.org/1wi0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wi0 RCSB], [https://www.ebi.ac.uk/pdbsum/1wi0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wi0 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wi0 TOPSAN]</span></td></tr>
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[[Category: Kigawa, T.]]
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</table>
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[[Category: Koshiba, S.]]
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== Function ==
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[https://www.uniprot.org/uniprot/MP2K5_MOUSE MP2K5_MOUSE] Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis.<ref>PMID:10473620</ref> <ref>PMID:16507987</ref>
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[[Category: Tochio, N.]]
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[[Category: Yokoyama, S.]]
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[[Category: Yoneyama, M.]]
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[[Category: cytoplasmic signalling]]
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[[Category: pb1 domain]]
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[[Category: protein-protein interaction site]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: rsgi]]
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[[Category: structural genomics]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:44:33 2008''
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==See Also==
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*[[Mitogen-activated protein kinase kinase 3D structures|Mitogen-activated protein kinase kinase 3D structures]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Hayashi F]]
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[[Category: Inoue M]]
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[[Category: Kigawa T]]
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[[Category: Koshiba S]]
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[[Category: Tochio N]]
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[[Category: Yokoyama S]]
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[[Category: Yoneyama M]]

Current revision

Solution structure of the PB1 domain of mouse mitogen activated protein kinase kinase 5 (MAP2K5)

PDB ID 1wi0

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OCA

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