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1wkh

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[[Image:1wkh.gif|left|200px]]<br /><applet load="1wkh" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1wkh, resolution 2.25&Aring;" />
 
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'''Acetylornithine aminotransferase from thermus thermophilus HB8'''<br />
 
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==About this Structure==
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==Acetylornithine aminotransferase from thermus thermophilus HB8==
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1WKH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=PPE:'>PPE</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Acetylornithine_transaminase Acetylornithine transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.11 2.6.1.11] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WKH OCA].
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<StructureSection load='1wkh' size='340' side='right'caption='[[1wkh]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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[[Category: Acetylornithine transaminase]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[1wkh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WKH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WKH FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PPE:4-[(1,3-DICARBOXY-PROPYLAMINO)-METHYL]-3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDINIUM'>PPE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wkh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wkh OCA], [https://pdbe.org/1wkh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wkh RCSB], [https://www.ebi.ac.uk/pdbsum/1wkh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wkh ProSAT], [https://www.topsan.org/Proteins/RSGI/1wkh TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LYSJ_THET8 LYSJ_THET8] Catalyzes the transfer of the amino group of L-glutamate to [LysW]-aminoadipate 6-semialdehyde, generating [LysW]-gamma-L-lysine.[HAMAP-Rule:MF_02084]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wk/1wkh_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wkh ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: Goto, M.]]
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[[Category: Goto M]]
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[[Category: Hirotsu, K.]]
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[[Category: Hirotsu K]]
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[[Category: Matsumura, M.]]
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[[Category: Matsumura M]]
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[[Category: Miyahara, I.]]
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[[Category: Miyahara I]]
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[[Category: Omi, R.]]
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[[Category: Omi R]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: PPE]]
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[[Category: aminotransferase]]
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[[Category: plp]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: rsgi]]
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[[Category: structural genomics]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:45:22 2008''
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Current revision

Acetylornithine aminotransferase from thermus thermophilus HB8

PDB ID 1wkh

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