2fs5
From Proteopedia
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- | [[Image:2fs5.png|left|200px]] | ||
- | + | ==Crystal structure of TDP-fucosamine acetyltransferase (WecD)- apo form== | |
- | + | <StructureSection load='2fs5' size='340' side='right'caption='[[2fs5]], [[Resolution|resolution]] 1.95Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2fs5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_CFT073 Escherichia coli CFT073]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FS5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FS5 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
- | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fs5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fs5 OCA], [https://pdbe.org/2fs5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fs5 RCSB], [https://www.ebi.ac.uk/pdbsum/2fs5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fs5 ProSAT]</span></td></tr> |
- | [[2fs5]] is a 2 chain structure with sequence from [ | + | </table> |
- | + | == Function == | |
- | == | + | [https://www.uniprot.org/uniprot/WECD_ECOL6 WECD_ECOL6] Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA).[HAMAP-Rule:MF_02027]<ref>PMID:16855251</ref> |
- | < | + | == Evolutionary Conservation == |
- | [[ | + | [[Image:Consurf_key_small.gif|200px|right]] |
- | [[ | + | Check<jmol> |
- | [ | + | <jmolCheckbox> |
- | [[ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fs/2fs5_consurf.spt"</scriptWhenChecked> |
- | [ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
- | [[ | + | <text>to colour the structure by Evolutionary Conservation</text> |
- | [[Category: | + | </jmolCheckbox> |
- | [[Category: | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fs5 ConSurf]. |
- | [[Category: | + | <div style="clear:both"></div> |
- | [[Category: | + | == References == |
- | [[Category: | + | <references/> |
- | [[Category: | + | __TOC__ |
- | [[Category: | + | </StructureSection> |
- | [[Category: | + | [[Category: Escherichia coli CFT073]] |
- | [[Category: | + | [[Category: Large Structures]] |
+ | [[Category: Cygler M]] | ||
+ | [[Category: Hung MN]] | ||
+ | [[Category: Matte A]] | ||
+ | [[Category: Munger C]] | ||
+ | [[Category: Nadeau G]] | ||
+ | [[Category: Rangarajan E]] | ||
+ | [[Category: Sulea T]] |
Current revision
Crystal structure of TDP-fucosamine acetyltransferase (WecD)- apo form
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