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2gtd
From Proteopedia
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| - | [[Image:2gtd.png|left|200px]] | ||
| - | + | ==Crystal Structure of a Type III Pantothenate Kinase: Insight into the Catalysis of an Essential Coenzyme A Biosynthetic Enzyme Universally Distributed in Bacteria== | |
| - | + | <StructureSection load='2gtd' size='340' side='right'caption='[[2gtd]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2gtd]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GTD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GTD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gtd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gtd OCA], [https://pdbe.org/2gtd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gtd RCSB], [https://www.ebi.ac.uk/pdbsum/2gtd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gtd ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[2gtd]] is a 6 chain structure with sequence from [ | + | == Function == |
| + | [https://www.uniprot.org/uniprot/COAX_THEMA COAX_THEMA] Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.<ref>PMID:16855243</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gt/2gtd_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gtd ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Pantothenate kinase|Pantothenate kinase]] | + | *[[Pantothenate kinase 3D structures|Pantothenate kinase 3D structures]] |
| - | + | == References == | |
| - | == | + | <references/> |
| - | < | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Thermotoga maritima]] | [[Category: Thermotoga maritima]] | ||
| - | [[Category: Brand | + | [[Category: Brand AL]] |
| - | [[Category: Eyobo | + | [[Category: Eyobo Y]] |
| - | [[Category: Martynowski | + | [[Category: Martynowski D]] |
| - | [[Category: Tomchick | + | [[Category: Tomchick D]] |
| - | [[Category: Yang | + | [[Category: Yang K]] |
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of a Type III Pantothenate Kinase: Insight into the Catalysis of an Essential Coenzyme A Biosynthetic Enzyme Universally Distributed in Bacteria
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