2ke7

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[[Image:2ke7.png|left|200px]]
 
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{{STRUCTURE_2ke7| PDB=2ke7 | SCENE= }}
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==NMR structure of the first SAM domain from AIDA1==
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<StructureSection load='2ke7' size='340' side='right'caption='[[2ke7]]' scene=''>
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===NMR structure of the first SAM domain from AIDA1===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2ke7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KE7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KE7 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ke7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ke7 OCA], [https://pdbe.org/2ke7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ke7 RCSB], [https://www.ebi.ac.uk/pdbsum/2ke7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ke7 ProSAT]</span></td></tr>
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[[2ke7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KE7 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ANS1B_HUMAN ANS1B_HUMAN] Isoform 2 may participate in the regulation of nucleoplasmic coilin protein interactions in neuronal and transformed cells.<ref>PMID:15862129</ref> <ref>PMID:15347684</ref> Isoform 3 can regulate global protein synthesis by altering nucleolar numbers (By similarity).<ref>PMID:15862129</ref> <ref>PMID:15347684</ref> Isoform 4 may play a role as a modulator of APP processing. Overexpression can down-regulate APP processing.<ref>PMID:15862129</ref> <ref>PMID:15347684</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ke/2ke7_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ke7 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Donaldson, L.]]
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[[Category: Large Structures]]
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[[Category: Ank repeat]]
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[[Category: Donaldson L]]
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[[Category: Cell junction]]
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[[Category: Cell membrane]]
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[[Category: Cell projection]]
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[[Category: Membrane]]
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[[Category: Nucleus]]
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[[Category: Phosphoprotein]]
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[[Category: Postsynaptic cell membrane]]
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[[Category: Protein binding]]
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[[Category: Sam domain]]
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[[Category: Synapse]]
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Current revision

NMR structure of the first SAM domain from AIDA1

PDB ID 2ke7

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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