This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2ksp
From Proteopedia
(Difference between revisions)
| (8 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2ksp.png|left|200px]] | ||
| - | + | ==Mechanism for the selective interaction of C-terminal EH-domain proteins with specific NPF-containing partners== | |
| - | + | <StructureSection load='2ksp' size='340' side='right'caption='[[2ksp]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2ksp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KSP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KSP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ksp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ksp OCA], [https://pdbe.org/2ksp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ksp RCSB], [https://www.ebi.ac.uk/pdbsum/2ksp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ksp ProSAT]</span></td></tr> |
| - | [[2ksp]] is a 2 chain structure with sequence from [ | + | </table> |
| - | + | == Function == | |
| - | == | + | [https://www.uniprot.org/uniprot/EHD1_HUMAN EHD1_HUMAN] Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes.<ref>PMID:15020713</ref> <ref>PMID:17233914</ref> |
| - | < | + | == Evolutionary Conservation == |
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ks/2ksp_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ksp ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Caplan | + | [[Category: Large Structures]] |
| - | [[Category: Giridharan | + | [[Category: Caplan S]] |
| - | [[Category: Jovic | + | [[Category: Giridharan SS]] |
| - | [[Category: Kieken | + | [[Category: Jovic M]] |
| - | [[Category: Naslavsky | + | [[Category: Kieken F]] |
| - | [[Category: Sharma | + | [[Category: Naslavsky N]] |
| - | [[Category: Sorgen | + | [[Category: Sharma M]] |
| - | + | [[Category: Sorgen PL]] | |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Mechanism for the selective interaction of C-terminal EH-domain proteins with specific NPF-containing partners
| |||||||||||
Categories: Homo sapiens | Large Structures | Caplan S | Giridharan SS | Jovic M | Kieken F | Naslavsky N | Sharma M | Sorgen PL
