2ksp
From Proteopedia
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| - | [[Image:2ksp.png|left|200px]] | ||
| - | + | ==Mechanism for the selective interaction of C-terminal EH-domain proteins with specific NPF-containing partners== | |
| - | + | <StructureSection load='2ksp' size='340' side='right'caption='[[2ksp]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2ksp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KSP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KSP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ksp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ksp OCA], [https://pdbe.org/2ksp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ksp RCSB], [https://www.ebi.ac.uk/pdbsum/2ksp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ksp ProSAT]</span></td></tr> |
| - | [[2ksp]] is a 2 chain structure with sequence from [ | + | </table> |
| - | + | == Function == | |
| - | == | + | [https://www.uniprot.org/uniprot/EHD1_HUMAN EHD1_HUMAN] Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes.<ref>PMID:15020713</ref> <ref>PMID:17233914</ref> |
| - | < | + | == Evolutionary Conservation == |
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ks/2ksp_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ksp ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Caplan | + | [[Category: Large Structures]] |
| - | [[Category: Giridharan | + | [[Category: Caplan S]] |
| - | [[Category: Jovic | + | [[Category: Giridharan SS]] |
| - | [[Category: Kieken | + | [[Category: Jovic M]] |
| - | [[Category: Naslavsky | + | [[Category: Kieken F]] |
| - | [[Category: Sharma | + | [[Category: Naslavsky N]] |
| - | [[Category: Sorgen | + | [[Category: Sharma M]] |
| - | + | [[Category: Sorgen PL]] | |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Mechanism for the selective interaction of C-terminal EH-domain proteins with specific NPF-containing partners
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Categories: Homo sapiens | Large Structures | Caplan S | Giridharan SS | Jovic M | Kieken F | Naslavsky N | Sharma M | Sorgen PL
