This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2ima

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:03, 21 February 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2ima.png|left|200px]]
 
-
{{STRUCTURE_2ima| PDB=2ima | SCENE= }}
+
==Clostridium botulinum Neurotoxin Serotype A Light Chain Inhibited by 2,4-dichlorocinnamic hydroxamate==
 +
<StructureSection load='2ima' size='340' side='right'caption='[[2ima]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[2ima]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_botulinum Clostridium botulinum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IMA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IMA FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GB4:(2E)-3-(2,4-DICHLOROPHENYL)-N-HYDROXYACRYLAMIDE'>GB4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ima FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ima OCA], [https://pdbe.org/2ima PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ima RCSB], [https://www.ebi.ac.uk/pdbsum/2ima PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ima ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q84GJ4_CLOBO Q84GJ4_CLOBO]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/im/2ima_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ima ConSurf].
 +
<div style="clear:both"></div>
-
===Clostridium botulinum Neurotoxin Serotype A Light Chain Inhibited by 2,4-dichlorocinnamic hydroxamate===
+
==See Also==
-
 
+
*[[Botulinum neurotoxin 3D structures|Botulinum neurotoxin 3D structures]]
-
{{ABSTRACT_PUBMED_17524984}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
-
[[2ima]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_botulinum Clostridium botulinum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IMA OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:017524984</ref><references group="xtra"/>
+
-
[[Category: Bontoxilysin]]
+
[[Category: Clostridium botulinum]]
[[Category: Clostridium botulinum]]
-
[[Category: Allen, K N.]]
+
[[Category: Large Structures]]
-
[[Category: Silvaggi, N R.]]
+
[[Category: Allen KN]]
-
[[Category: Clostridium botulinum neurotoxin serotype some]]
+
[[Category: Silvaggi NR]]
-
[[Category: Hydrolase]]
+
-
[[Category: Protease inhibitor]]
+
-
[[Category: Substrate specificity]]
+
-
[[Category: Substrate switching]]
+

Current revision

Clostridium botulinum Neurotoxin Serotype A Light Chain Inhibited by 2,4-dichlorocinnamic hydroxamate

PDB ID 2ima

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools