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2kjy

From Proteopedia

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[[Image:2kjy.png|left|200px]]
 
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{{STRUCTURE_2kjy| PDB=2kjy | SCENE= }}
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==MYPT1(658-714)==
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<StructureSection load='2kjy' size='340' side='right'caption='[[2kjy]]' scene=''>
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===MYPT1(658-714)===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2kjy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KJY FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kjy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kjy OCA], [https://pdbe.org/2kjy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kjy RCSB], [https://www.ebi.ac.uk/pdbsum/2kjy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kjy ProSAT]</span></td></tr>
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[[2kjy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJY OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/MYPT1_HUMAN MYPT1_HUMAN] Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.<ref>PMID:19245366</ref> <ref>PMID:18477460</ref> <ref>PMID:20354225</ref>
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<ref group="xtra">PMID:019701943</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kj/2kjy_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kjy ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Eto, M.]]
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[[Category: Large Structures]]
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[[Category: Iwaoka, R.]]
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[[Category: Eto M]]
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[[Category: Mori, S.]]
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[[Category: Iwaoka R]]
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[[Category: Ohki, S.]]
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[[Category: Mori S]]
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[[Category: Ank repeat]]
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[[Category: Ohki S]]
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[[Category: Myosin phosphatase]]
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[[Category: Mypt1]]
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[[Category: Phosphoprotein]]
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[[Category: Phosphorylation]]
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[[Category: Protein phosphatase 1]]
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[[Category: Signaling protein]]
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Current revision

MYPT1(658-714)

PDB ID 2kjy

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