2fts

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[[Image:2fts.png|left|200px]]
 
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{{STRUCTURE_2fts| PDB=2fts | SCENE= }}
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==Crystal structure of the glycine receptor-gephyrin complex==
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<StructureSection load='2fts' size='340' side='right'caption='[[2fts]], [[Resolution|resolution]] 2.41&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2fts]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FTS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FTS FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.41&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fts FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fts OCA], [https://pdbe.org/2fts PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fts RCSB], [https://www.ebi.ac.uk/pdbsum/2fts PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fts ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GEPH_RAT GEPH_RAT] Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.<ref>PMID:8264797</ref> <ref>PMID:9990024</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ft/2fts_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fts ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of the glycine receptor-gephyrin complex===
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==See Also==
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*[[Gephyrin|Gephyrin]]
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{{ABSTRACT_PUBMED_16511563}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[2fts]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FTS OCA].
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</StructureSection>
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[[Category: Large Structures]]
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==Reference==
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<ref group="xtra">PMID:016511563</ref><references group="xtra"/>
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[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Kim, E Y.]]
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[[Category: Kim EY]]
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[[Category: Schindelin, H.]]
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[[Category: Schindelin H]]
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[[Category: Gephyrin]]
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[[Category: Glycine receptor]]
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[[Category: Neuroreceptor anchoring]]
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[[Category: Structural protein]]
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Current revision

Crystal structure of the glycine receptor-gephyrin complex

PDB ID 2fts

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