2fol

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[[Image:2fol.png|left|200px]]
 
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{{STRUCTURE_2fol| PDB=2fol | SCENE= }}
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==Crystal structure of human RAB1A in complex with GDP==
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<StructureSection load='2fol' size='340' side='right'caption='[[2fol]], [[Resolution|resolution]] 2.63&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2fol]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FOL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FOL FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.631&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fol FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fol OCA], [https://pdbe.org/2fol PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fol RCSB], [https://www.ebi.ac.uk/pdbsum/2fol PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fol ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RAB1A_HUMAN RAB1A_HUMAN] Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fo/2fol_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fol ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of human RAB1A in complex with GDP===
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==See Also==
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*[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]]
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{{ABSTRACT_PUBMED_15608370}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[2fol]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FOL OCA].
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==Reference==
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<ref group="xtra">PMID:015608370</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C.]]
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[[Category: Large Structures]]
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[[Category: Bochkarev, A.]]
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[[Category: Arrowsmith C]]
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[[Category: Edwards, A.]]
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[[Category: Bochkarev A]]
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[[Category: Park, H.]]
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[[Category: Edwards A]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Park H]]
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[[Category: Shen, L.]]
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[[Category: Shen L]]
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[[Category: Shen, Y.]]
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[[Category: Shen Y]]
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[[Category: Sundstrom, M.]]
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[[Category: Sundstrom M]]
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[[Category: Tempel, W.]]
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[[Category: Tempel W]]
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[[Category: Wang, J.]]
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[[Category: Wang J]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt J]]
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[[Category: G-protein]]
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[[Category: Gtp analogue]]
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[[Category: Protein transport]]
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[[Category: Rab]]
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[[Category: Sgc]]
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[[Category: Struct ural genomics consortium]]
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[[Category: Structural genomic]]
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[[Category: Structural genomics consortium]]
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Current revision

Crystal structure of human RAB1A in complex with GDP

PDB ID 2fol

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