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2fl9

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[[Image:2fl9.png|left|200px]]
 
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{{STRUCTURE_2fl9| PDB=2fl9 | SCENE= }}
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==Evolution of bacteriophage tails: Structure of T4 gene product 10==
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<SX load='2fl9' size='340' side='right' viewer='molstar' caption='[[2fl9]], [[Resolution|resolution]] 17.00&Aring;' scene=''>
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===Evolution of bacteriophage tails: Structure of T4 gene product 10===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2fl9]] is a 18 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FL9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FL9 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_16554069}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 17&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fl9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fl9 OCA], [https://pdbe.org/2fl9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fl9 RCSB], [https://www.ebi.ac.uk/pdbsum/2fl9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fl9 ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[2fl9]] is a 18 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FL9 OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/BP10_BPT4 BP10_BPT4] Baseplate protein that is part of the baseplate wedge and that connects the short tail fibers to the baseplate (PubMed:16554069). During infection, the baseplate undergoes a conformational change from a dome-shaped to a star-shaped structure. At this point, gp10 rotates and acts as a lever that unfolds the short tail fibers, which then interact with host cell surface receptors. Involved in the tail assembly.<ref>PMID:16554069</ref> <ref>PMID:21129200</ref>
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==Reference==
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== Evolutionary Conservation ==
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<ref group="xtra">PMID:016554069</ref><references group="xtra"/>
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Enterobacteria phage t4]]
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Check<jmol>
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[[Category: Leiman, P G.]]
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<jmolCheckbox>
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[[Category: Mesyanzhinov, V V.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fl/2fl9_consurf.spt"</scriptWhenChecked>
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[[Category: Rossmann, M G.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Shneider, M M.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Bacteriophage t4]]
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</jmolCheckbox>
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[[Category: Baseplate]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fl9 ConSurf].
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[[Category: Evolution]]
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<div style="clear:both"></div>
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[[Category: Gp10]]
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== References ==
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[[Category: Structural comparison]]
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<references/>
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[[Category: Tail]]
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__TOC__
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[[Category: Virus-viral protein complex]]
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</SX>
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[[Category: Escherichia virus T4]]
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[[Category: Large Structures]]
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[[Category: Leiman PG]]
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[[Category: Mesyanzhinov VV]]
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[[Category: Rossmann MG]]
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[[Category: Shneider MM]]

Current revision

Evolution of bacteriophage tails: Structure of T4 gene product 10

2fl9, resolution 17.00Å

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