This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2hw4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:34, 14 February 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2hw4.png|left|200px]]
 
-
{{STRUCTURE_2hw4| PDB=2hw4 | SCENE= }}
+
==Crystal structure of human phosphohistidine phosphatase==
-
 
+
<StructureSection load='2hw4' size='340' side='right'caption='[[2hw4]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-
===Crystal structure of human phosphohistidine phosphatase===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[2hw4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HW4 FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_16990267}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hw4 OCA], [https://pdbe.org/2hw4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hw4 RCSB], [https://www.ebi.ac.uk/pdbsum/2hw4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hw4 ProSAT]</span></td></tr>
-
[[2hw4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HW4 OCA].
+
</table>
-
 
+
== Function ==
-
==Reference==
+
[https://www.uniprot.org/uniprot/PHP14_HUMAN PHP14_HUMAN] Exhibits phosphohistidine phosphatase activity.
-
<ref group="xtra">PMID:016990267</ref><references group="xtra"/>
+
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hw/2hw4_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hw4 ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Arrowsmith, C.]]
+
[[Category: Large Structures]]
-
[[Category: Berg, S Van Den.]]
+
[[Category: Arrowsmith C]]
-
[[Category: Berglund, H.]]
+
[[Category: Berglund H]]
-
[[Category: Busam, R D.]]
+
[[Category: Busam RD]]
-
[[Category: Collins, R.]]
+
[[Category: Collins R]]
-
[[Category: Edwards, A.]]
+
[[Category: Edwards A]]
-
[[Category: Ehn, M.]]
+
[[Category: Ehn M]]
-
[[Category: Flodin, S.]]
+
[[Category: Flodin S]]
-
[[Category: Flores, A.]]
+
[[Category: Flores A]]
-
[[Category: Graslund, S.]]
+
[[Category: Graslund S]]
-
[[Category: Hallberg, B M.]]
+
[[Category: Hallberg BM]]
-
[[Category: Hammarstrom, M.]]
+
[[Category: Hammarstrom M]]
-
[[Category: Hogbom, M.]]
+
[[Category: Hogbom M]]
-
[[Category: Kotenyova, T.]]
+
[[Category: Holmberg Schiavone L]]
-
[[Category: Nilsson-Ehle, P.]]
+
[[Category: Kotenyova T]]
-
[[Category: Nordlund, P.]]
+
[[Category: Nilsson-Ehle P]]
-
[[Category: Nyman, T.]]
+
[[Category: Nordlund P]]
-
[[Category: Ogg, D.]]
+
[[Category: Nyman T]]
-
[[Category: Persson, C.]]
+
[[Category: Ogg D]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Persson C]]
-
[[Category: Schiavone, L Holmberg.]]
+
[[Category: Stenmark P]]
-
[[Category: Stenmark, P.]]
+
[[Category: Sundstrom M]]
-
[[Category: Sundstrom, M.]]
+
[[Category: Thorsell AG]]
-
[[Category: Thorsell, A G.]]
+
[[Category: Uppenberg J]]
-
[[Category: Uppenberg, J.]]
+
[[Category: Van Den Berg S]]
-
[[Category: Weigelt, J.]]
+
[[Category: Weigelt J]]
-
[[Category: Human]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Phosphatase]]
+
-
[[Category: Phosphohistidine]]
+
-
[[Category: Phpt1]]
+
-
[[Category: Sgc]]
+
-
[[Category: Structural genomic]]
+
-
[[Category: Structural genomics consortium]]
+

Current revision

Crystal structure of human phosphohistidine phosphatase

PDB ID 2hw4

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2hw4"
Personal tools