2l2m

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2l2m" [edit=sysop:move=sysop])
Current revision (06:51, 1 May 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2l2m.png|left|200px]]
 
-
{{STRUCTURE_2l2m| PDB=2l2m | SCENE= }}
+
==Solution structure of the second dsRBD of HYL1==
-
 
+
<StructureSection load='2l2m' size='340' side='right'caption='[[2l2m]]' scene=''>
-
===Solution structure of the second dsRBD of HYL1===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[2l2m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L2M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L2M FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_20735118}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
 
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l2m OCA], [https://pdbe.org/2l2m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l2m RCSB], [https://www.ebi.ac.uk/pdbsum/2l2m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l2m ProSAT]</span></td></tr>
-
==About this Structure==
+
</table>
-
[[2l2m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L2M OCA].
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/DRB1_ARATH DRB1_ARATH] Double-stranded RNA-binding protein involved in RNA-mediated post-transcriptional gene silencing (PTGS). Functions in the microRNAs (miRNAs) biogenesis by assisting DICER-LIKE 1 (DCL1) in the accurate processing from primary miRNAs (pri-miRNAs) to miRNAs in the nucleus. Forms a complex with SERRATE (SE) and DCL1 to promote accurate processing of pri-miRNAs by DCL1. Binds and assist DCL1 for accurate processing of precursor miRNAs (pre-miRNA). Indirectly involved in the production of trans-acting small interfering RNAs (ta-siRNAs) derived from the TAS1, TAS2 or TAS3 endogenous transcripts by participating in the production of their initiating miRNAs. Involved with argonaute 1 (AGO1) in the guide strand selection from miRNA duplexes, presumably by directional loading of the miRNA duplex (guide stand and passenger strand) onto the RNA-induced silencing complex (RISC) for passenger strand degradation. Does not participate in sense transgene-induced post-transcriptional gene silencing (S-PTGS). Involved in several plant development aspects and response to hormones through its role in miRNAs processing.<ref>PMID:11148283</ref> <ref>PMID:14722360</ref> <ref>PMID:14972688</ref> <ref>PMID:15821876</ref> <ref>PMID:16428603</ref> <ref>PMID:16889646</ref> <ref>PMID:17337628</ref> <ref>PMID:18632569</ref> <ref>PMID:19304749</ref> <ref>PMID:19861421</ref> <ref>PMID:20462493</ref> <ref>PMID:20735118</ref>
-
==Reference==
+
== Evolutionary Conservation ==
-
<ref group="xtra">PMID:020735118</ref><references group="xtra"/>
+
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l2/2l2m_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2l2m ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
-
[[Category: Boisbouvier, J.]]
+
[[Category: Large Structures]]
-
[[Category: Bologna, N G.]]
+
[[Category: Boisbouvier J]]
-
[[Category: Burdisso, P.]]
+
[[Category: Bologna NG]]
-
[[Category: Imbert, L.]]
+
[[Category: Burdisso P]]
-
[[Category: Mateos, J L.]]
+
[[Category: Imbert L]]
-
[[Category: Palatnik, J F.]]
+
[[Category: Mateos JL]]
-
[[Category: Rasia, R M.]]
+
[[Category: Palatnik JF]]
-
[[Category: Dsrbd]]
+
[[Category: Rasia RM]]
-
[[Category: Mirna]]
+
-
[[Category: Plant protein]]
+
-
[[Category: Rna binding protein]]
+

Current revision

Solution structure of the second dsRBD of HYL1

PDB ID 2l2m

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2l2m"
Personal tools