This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2jvg
From Proteopedia
(Difference between revisions)
m (Protected "2jvg" [edit=sysop:move=sysop]) |
|||
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2jvg.png|left|200px]] | ||
| - | + | ==Structure of C3-binding domain 4 of Staphylococcus aureus protein Sbi== | |
| - | + | <StructureSection load='2jvg' size='340' side='right'caption='[[2jvg]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2jvg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JVG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JVG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jvg OCA], [https://pdbe.org/2jvg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jvg RCSB], [https://www.ebi.ac.uk/pdbsum/2jvg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jvg ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[2jvg]] is a 1 chain structure with sequence from [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/SBI_STAAM SBI_STAAM] Plays a role in the inhibition of both the innate and adaptive immune responses. Possesses two N-terminal domains that bind the Fc region of IgG and two domains that form a tripartite complex with complement factors C3b and CFH. By recruiting CFH and C3b, the secreted form acts as a potent complement inhibitor of the alternative pathway-mediated lysis.[UniProtKB:A6QJQ7]<ref>PMID:18550524</ref> | |
| - | == | + | == References == |
| - | < | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Staphylococcus aureus]] | [[Category: Staphylococcus aureus]] | ||
| - | [[Category: Bagby | + | [[Category: Bagby S]] |
| - | [[Category: Burman | + | [[Category: Burman J]] |
| - | [[Category: Clark | + | [[Category: Clark EA]] |
| - | + | [[Category: Upadhyay A]] | |
| - | [[Category: Upadhyay | + | [[Category: Van den Elsen JMH]] |
| - | [[Category: | + | |
| - | + | ||
Current revision
Structure of C3-binding domain 4 of Staphylococcus aureus protein Sbi
| |||||||||||
