2jup
From Proteopedia
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- | [[Image:2jup.png|left|200px]] | ||
- | + | ==FBP28WW2 domain in complex with the PPLIPPPP peptide== | |
- | + | <StructureSection load='2jup' size='340' side='right'caption='[[2jup]]' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2jup]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JUP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JUP FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jup OCA], [https://pdbe.org/2jup PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jup RCSB], [https://www.ebi.ac.uk/pdbsum/2jup PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jup ProSAT]</span></td></tr> | |
- | == | + | </table> |
- | [[2jup]] is a 2 chain structure with sequence from [ | + | == Function == |
- | + | [https://www.uniprot.org/uniprot/TCRG1_MOUSE TCRG1_MOUSE] Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner (By similarity). | |
- | == | + | == Evolutionary Conservation == |
- | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ju/2jup_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jup ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
- | [[Category: Macias | + | [[Category: Synthetic construct]] |
- | [[Category: Martin-Malpartida | + | [[Category: Macias MJ]] |
- | [[Category: Oschkinat | + | [[Category: Martin-Malpartida P]] |
- | [[Category: Ramirez-Espain | + | [[Category: Oschkinat H]] |
- | [[Category: Ruiz | + | [[Category: Ramirez-Espain X]] |
- | + | [[Category: Ruiz L]] | |
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Current revision
FBP28WW2 domain in complex with the PPLIPPPP peptide
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