2is9

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2is9" [edit=sysop:move=sysop])
Current revision (13:53, 13 March 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2is9.png|left|200px]]
 
-
{{STRUCTURE_2is9| PDB=2is9 | SCENE= }}
+
==Structure of yeast DCN-1==
-
 
+
<StructureSection load='2is9' size='340' side='right'caption='[[2is9]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
-
===Structure of yeast DCN-1===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[2is9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IS9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IS9 FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_17597076}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PT:PLATINUM+(II)+ION'>PT</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2is9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2is9 OCA], [https://pdbe.org/2is9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2is9 RCSB], [https://www.ebi.ac.uk/pdbsum/2is9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2is9 ProSAT]</span></td></tr>
-
[[2is9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IS9 OCA].
+
</table>
-
 
+
== Function ==
-
==Reference==
+
[https://www.uniprot.org/uniprot/DCN1_YEAST DCN1_YEAST] Required for neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. Does not act by preventing deneddylation, but rather facilitates neddylation, possibly by acting with HRT1/RBX1 to recruit the Nedd8-charged E2 UBC12 to the cullin component of SCF-type complexes.<ref>PMID:15988528</ref>
-
<ref group="xtra">PMID:017597076</ref><references group="xtra"/>
+
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/is/2is9_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2is9 ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
-
[[Category: Gao, J.]]
+
[[Category: Gao J]]
-
[[Category: Gong, W.]]
+
[[Category: Gong W]]
-
[[Category: Liu, Y.]]
+
[[Category: Liu Y]]
-
[[Category: Rao, Z.]]
+
[[Category: Rao Z]]
-
[[Category: Sun, L.]]
+
[[Category: Sun L]]
-
[[Category: Wei, Z.]]
+
[[Category: Wei Z]]
-
[[Category: Xu, R M.]]
+
[[Category: Xu RM]]
-
[[Category: Yang, X.]]
+
[[Category: Yang X]]
-
[[Category: Zhou, J.]]
+
[[Category: Zhou J]]
-
[[Category: Dcn1]]
+
-
[[Category: Transcription]]
+
-
[[Category: Ubiquitin]]
+

Current revision

Structure of yeast DCN-1

PDB ID 2is9

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2is9"
Personal tools