This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1x0a

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:03, 25 October 2023) (edit) (undo)
 
(15 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1x0a.gif|left|200px]]<br /><applet load="1x0a" size="350" color="white" frame="true" align="right" spinBox="true"
 
-
caption="1x0a, resolution 2.00&Aring;" />
 
-
'''Crystal Structure of type II malate/lactate dehydrogenase from thermus thermophilus HB8'''<br />
 
-
==About this Structure==
+
==Crystal Structure of type II malate/lactate dehydrogenase from thermus thermophilus HB8==
-
1X0A is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=NA:'>NA</scene> and <scene name='pdbligand=FMT:'>FMT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X0A OCA].
+
<StructureSection load='1x0a' size='340' side='right'caption='[[1x0a]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-
[[Category: L-lactate dehydrogenase]]
+
== Structural highlights ==
-
[[Category: Single protein]]
+
<table><tr><td colspan='2'>[[1x0a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X0A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X0A FirstGlance]. <br>
-
[[Category: Thermus thermophilus]]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
[[Category: Kunishima, N.]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-
[[Category: Mizutani, H.]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x0a OCA], [https://pdbe.org/1x0a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x0a RCSB], [https://www.ebi.ac.uk/pdbsum/1x0a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x0a ProSAT], [https://www.topsan.org/Proteins/RSGI/1x0a TOPSAN]</span></td></tr>
-
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+
</table>
-
[[Category: FMT]]
+
== Function ==
-
[[Category: NA]]
+
[https://www.uniprot.org/uniprot/Q53W84_THET8 Q53W84_THET8]
-
[[Category: malate dehydrogenase]]
+
== Evolutionary Conservation ==
-
[[Category: riken structural genomics/proteomics initiative]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: rsgi]]
+
Check<jmol>
-
[[Category: structural genomics]]
+
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x0/1x0a_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x0a ConSurf].
 +
<div style="clear:both"></div>
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:49:49 2008''
+
==See Also==
 +
*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Thermus thermophilus HB8]]
 +
[[Category: Kunishima N]]
 +
[[Category: Mizutani H]]

Current revision

Crystal Structure of type II malate/lactate dehydrogenase from thermus thermophilus HB8

PDB ID 1x0a

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools