3co8

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[[Image:3co8.png|left|200px]]
 
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{{STRUCTURE_3co8| PDB=3co8 | SCENE= }}
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==Crystal structure of alanine racemase from Oenococcus oeni==
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<StructureSection load='3co8' size='340' side='right'caption='[[3co8]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CO8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CO8 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3co8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3co8 OCA], [https://pdbe.org/3co8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3co8 RCSB], [https://www.ebi.ac.uk/pdbsum/3co8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3co8 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3co8 TOPSAN]</span></td></tr>
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</table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/co/3co8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3co8 ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The crystal structure of alanine racemase from Oenococcus oeni has been determined at 1.7 A resolution using the single-wavelength anomalous dispersion (SAD) method and selenium-labelled protein. The protein exists as a symmetric dimer in the crystal, with both protomers contributing to the two active sites. Pyridoxal 5'-phosphate, a cofactor, is bound to each monomer and forms a Schiff base with Lys39. Structural comparison of alanine racemase from O. oeni (Alr) with homologous family members revealed similar domain organization and cofactor binding.
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===Crystal structure of alanine racemase from Oenococcus oeni===
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Structure of alanine racemase from Oenococcus oeni with bound pyridoxal 5'-phosphate.,Palani K, Burley SK, Swaminathan S Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jan 1;69(Pt 1):15-9. doi: , 10.1107/S1744309112047276. Epub 2012 Dec 25. PMID:23295479<ref>PMID:23295479</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3co8" style="background-color:#fffaf0;"></div>
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==About this Structure==
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==See Also==
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[[3co8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Oenococcus_oeni_psu-1 Oenococcus oeni psu-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CO8 OCA].
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*[[Alanine racemase 3D structures|Alanine racemase 3D structures]]
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[[Category: Alanine racemase]]
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== References ==
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[[Category: Oenococcus oeni psu-1]]
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<references/>
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[[Category: Burley, S K.]]
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__TOC__
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics.]]
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</StructureSection>
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[[Category: Palani, K.]]
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[[Category: Large Structures]]
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[[Category: Swaminathan, S.]]
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[[Category: Burley SK]]
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[[Category: 11082i]]
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[[Category: Palani K]]
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[[Category: Alanine racemase]]
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[[Category: Swaminathan S]]
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[[Category: Isomerase]]
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[[Category: New york sgx research center for structural genomic]]
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[[Category: Nysgxrc]]
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[[Category: Plp]]
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[[Category: Protein structure initiative ii]]
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[[Category: Psi-ii]]
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[[Category: Pyridoxal phosphate]]
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[[Category: Structural genomic]]
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[[Category: Tim barrel]]
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Current revision

Crystal structure of alanine racemase from Oenococcus oeni

PDB ID 3co8

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