2r2y

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2r2y" [edit=sysop:move=sysop])
Current revision (09:19, 21 February 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2r2y.png|left|200px]]
 
-
{{STRUCTURE_2r2y| PDB=2r2y | SCENE= }}
+
==Crystal structure of the proteasomal Rpn13 PRU-domain==
-
 
+
<StructureSection load='2r2y' size='340' side='right'caption='[[2r2y]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
-
===Crystal structure of the proteasomal Rpn13 PRU-domain===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[2r2y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R2Y FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_18497827}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-
 
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r2y OCA], [https://pdbe.org/2r2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r2y RCSB], [https://www.ebi.ac.uk/pdbsum/2r2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r2y ProSAT]</span></td></tr>
-
==About this Structure==
+
</table>
-
[[2r2y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R2Y OCA].
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/ADRM1_MOUSE ADRM1_MOUSE] Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity.<ref>PMID:15819879</ref> <ref>PMID:18497827</ref>
-
==Reference==
+
== Evolutionary Conservation ==
-
<ref group="xtra">PMID:018497827</ref><references group="xtra"/>
+
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r2/2r2y_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r2y ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Dikic, I.]]
+
[[Category: Dikic I]]
-
[[Category: Finley, D.]]
+
[[Category: Finley D]]
-
[[Category: Groll, M.]]
+
[[Category: Groll M]]
-
[[Category: Walters, K.]]
+
[[Category: Walters K]]
-
[[Category: 19s regulator]]
+
-
[[Category: Ph-domain]]
+
-
[[Category: Proteasome]]
+
-
[[Category: Protein binding]]
+
-
[[Category: Receptor]]
+
-
[[Category: Receptor domain for ubiquitin and proteasome binding]]
+
-
[[Category: Ubiquitin]]
+
-
[[Category: Ubiquitin-proteasome-degradation pathway]]
+

Current revision

Crystal structure of the proteasomal Rpn13 PRU-domain

PDB ID 2r2y

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools