2gdf
From Proteopedia
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- | [[Image:2gdf.png|left|200px]] | ||
- | + | ==Crystal structure of Dioclea violacea seed lectin== | |
- | + | <StructureSection load='2gdf' size='340' side='right'caption='[[2gdf]], [[Resolution|resolution]] 2.40Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2gdf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Macropsychanthus_violaceus Macropsychanthus violaceus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GDF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GDF FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |
- | == | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> |
- | [[2gdf]] is a 4 chain structure with sequence from [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gdf OCA], [https://pdbe.org/2gdf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gdf RCSB], [https://www.ebi.ac.uk/pdbsum/2gdf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gdf ProSAT]</span></td></tr> |
- | [[ | + | </table> |
- | [[ | + | == Function == |
- | [[ | + | [https://www.uniprot.org/uniprot/LECA_DIOGR LECA_DIOGR] D-mannose/D-glucose-binding lectin. Has anti-inflammatory activity in rats. Induces histamine release in mast cells from rat. Induces lymphocyte proliferation and IFNG production. Shows toxicity against the aquatic snail B.glabrata at concentrations higher than 50 ug/ml.<ref>PMID:1398779</ref> <ref>PMID:7524287</ref> <ref>PMID:18472821</ref> <ref>PMID:9575151</ref> <ref>PMID:10747944</ref> <ref>PMID:19765980</ref> |
- | [[ | + | == Evolutionary Conservation == |
- | [[Category: | + | [[Image:Consurf_key_small.gif|200px|right]] |
- | [[Category: | + | Check<jmol> |
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gd/2gdf_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gdf ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Macropsychanthus violaceus]] | ||
+ | [[Category: Cavada BS]] | ||
+ | [[Category: Chornet JJC]] | ||
+ | [[Category: Gallego del Sol F]] |
Current revision
Crystal structure of Dioclea violacea seed lectin
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