2rhg

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[[Image:2rhg.png|left|200px]]
 
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{{STRUCTURE_2rhg| PDB=2rhg | SCENE= }}
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==Tryptophan synthase complexed with IGP, pH 7.0, internal aldimine==
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<StructureSection load='2rhg' size='340' side='right'caption='[[2rhg]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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===Tryptophan synthase complexed with IGP, pH 7.0, internal aldimine===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2rhg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RHG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RHG FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IGP:INDOLE-3-GLYCEROL+PHOSPHATE'>IGP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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[[2rhg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RHG OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rhg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rhg OCA], [https://pdbe.org/2rhg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rhg RCSB], [https://www.ebi.ac.uk/pdbsum/2rhg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rhg ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRPA_SALTY TRPA_SALTY] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rh/2rhg_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rhg ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Tryptophan synthase|Tryptophan synthase]]
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*[[Tryptophan synthase 3D structures|Tryptophan synthase 3D structures]]
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[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
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__TOC__
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[[Category: Tryptophan synthase]]
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</StructureSection>
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[[Category: Barends, T.]]
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[[Category: Large Structures]]
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[[Category: Kulik, V.]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
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[[Category: Schlichting, I.]]
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[[Category: Barends T]]
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[[Category: Allosteric enzyme]]
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[[Category: Kulik V]]
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[[Category: Amino-acid biosynthesis]]
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[[Category: Schlichting I]]
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[[Category: Aminoacid biosynthesis]]
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[[Category: Aromatic amino acid biosynthesis]]
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[[Category: Carbon-oxygen lyase]]
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[[Category: Lyase]]
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[[Category: Pyridoxal phosphate]]
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[[Category: Tryptophan biosynthesis]]
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Current revision

Tryptophan synthase complexed with IGP, pH 7.0, internal aldimine

PDB ID 2rhg

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