2pwb
From Proteopedia
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- | [[Image:2pwb.png|left|200px]] | ||
- | + | ==Crystal structure of the complex of proteinase K with coumarin at 1.9 A resolution== | |
+ | <StructureSection load='2pwb' size='340' side='right'caption='[[2pwb]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[2pwb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Parengyodontium_album Parengyodontium album]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PWB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PWB FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=COU:COUMARIN'>COU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pwb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pwb OCA], [https://pdbe.org/2pwb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pwb RCSB], [https://www.ebi.ac.uk/pdbsum/2pwb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pwb ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/PRTK_PARAQ PRTK_PARAQ] Hydrolyzes keratin at aromatic and hydrophobic residues. | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pw/2pwb_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pwb ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
- | == | + | ==See Also== |
- | + | *[[Proteinase 3D structures|Proteinase 3D structures]] | |
- | + | __TOC__ | |
- | + | </StructureSection> | |
- | [[ | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Parengyodontium album]] |
- | [[Category: | + | [[Category: Kaur P]] |
- | [[Category: Kaur | + | [[Category: Sharma S]] |
- | [[Category: Sharma | + | [[Category: Singh AK]] |
- | [[Category: Singh | + | [[Category: Singh N]] |
- | [[Category: Singh | + | [[Category: Singh TP]] |
- | [[Category: Singh | + | [[Category: Sinha M]] |
- | [[Category: Sinha | + | |
- | + | ||
- | + | ||
- | + |
Current revision
Crystal structure of the complex of proteinase K with coumarin at 1.9 A resolution
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Categories: Large Structures | Parengyodontium album | Kaur P | Sharma S | Singh AK | Singh N | Singh TP | Sinha M