2r1j

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[[Image:2r1j.png|left|200px]]
 
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{{STRUCTURE_2r1j| PDB=2r1j | SCENE= }}
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==Crystal Structure of the P22 c2 Repressor protein in complex with the synthetic operator 9T==
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<StructureSection load='2r1j' size='340' side='right'caption='[[2r1j]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
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===Crystal Structure of the P22 c2 Repressor protein in complex with the synthetic operator 9T===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2r1j]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_virus_P22 Salmonella virus P22]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R1J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R1J FirstGlance]. <br>
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{{ABSTRACT_PUBMED_18237194}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r1j OCA], [https://pdbe.org/2r1j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r1j RCSB], [https://www.ebi.ac.uk/pdbsum/2r1j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r1j ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[2r1j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_p22 Enterobacteria phage p22]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R1J OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/RPC2_BPP22 RPC2_BPP22] This protein allows the phage to reside inactively in the chromosome of its host bacterium. This lysogenic state is maintained by binding of regulatory protein C2 to the OR and OL operators, preventing transcription of proteins necessary for lytic development.
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==Reference==
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== Evolutionary Conservation ==
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<ref group="xtra">PMID:018237194</ref><references group="xtra"/>
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Enterobacteria phage p22]]
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Check<jmol>
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[[Category: Hsiao, C.]]
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<jmolCheckbox>
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[[Category: Koudelka, G B.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r1/2r1j_consurf.spt"</scriptWhenChecked>
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[[Category: Watkins, D.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Williams, L D.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Woods, K.]]
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</jmolCheckbox>
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[[Category: Dna-binding]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r1j ConSurf].
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[[Category: Helix-turn-helix]]
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<div style="clear:both"></div>
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[[Category: Protein-dna complex]]
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__TOC__
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[[Category: Repressor]]
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</StructureSection>
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[[Category: Transcription]]
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[[Category: Large Structures]]
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[[Category: Transcription regulation]]
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[[Category: Salmonella virus P22]]
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[[Category: Transcription-dna complex]]
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[[Category: Hsiao C]]
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[[Category: Koudelka GB]]
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[[Category: Watkins D]]
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[[Category: Williams LD]]
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[[Category: Woods K]]

Current revision

Crystal Structure of the P22 c2 Repressor protein in complex with the synthetic operator 9T

PDB ID 2r1j

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