1xc1

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[[Image:1xc1.gif|left|200px]]<br /><applet load="1xc1" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1xc1, resolution 1.51&Aring;" />
 
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'''Oxo Zirconium(IV) Cluster in the Ferric Binding Protein (FBP)'''<br />
 
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==About this Structure==
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==Oxo Zirconium(IV) Cluster in the Ferric Binding Protein (FBP)==
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1XC1 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Neisseria_gonorrhoeae Neisseria gonorrhoeae] with <scene name='pdbligand=ZRC:'>ZRC</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XC1 OCA].
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<StructureSection load='1xc1' size='340' side='right'caption='[[1xc1]], [[Resolution|resolution]] 1.51&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1xc1]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_gonorrhoeae Neisseria gonorrhoeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XC1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XC1 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.51&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZRC:OXO+ZIRCONIUM(IV)+CLUSTER'>ZRC</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xc1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xc1 OCA], [https://pdbe.org/1xc1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xc1 RCSB], [https://www.ebi.ac.uk/pdbsum/1xc1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xc1 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FBP_NEIGO FBP_NEIGO] This protein may be a central component in the iron-acquisition system.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xc/1xc1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xc1 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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==See Also==
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Assembly of an oxo-zirconium(IV) cluster in a protein cleft., Zhong W, Alexeev D, Harvey I, Guo M, Hunter DJ, Zhu H, Campopiano DJ, Sadler PJ, Angew Chem Int Ed Engl. 2004 Nov 12;43(44):5914-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15472987 15472987]
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*[[Ferric-binding protein|Ferric-binding protein]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Neisseria gonorrhoeae]]
[[Category: Neisseria gonorrhoeae]]
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[[Category: Single protein]]
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[[Category: Alexeev D]]
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[[Category: Alexeev, D.]]
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[[Category: Campopiano DJ]]
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[[Category: Campopiano, D J.]]
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[[Category: Guo M]]
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[[Category: Guo, M.]]
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[[Category: Harvey I]]
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[[Category: Harvey, I.]]
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[[Category: Hunter DJB]]
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[[Category: Hunter, D J.B.]]
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[[Category: Sadler PJ]]
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[[Category: Sadler, P J.]]
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[[Category: Zhong W]]
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[[Category: Zhong, W.]]
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[[Category: Zhu H]]
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[[Category: Zhu, H.]]
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[[Category: ZRC]]
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[[Category: metal-oxo cluster]]
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[[Category: periplasmic ferric binding protein]]
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[[Category: zirconium]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:53:17 2008''
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Current revision

Oxo Zirconium(IV) Cluster in the Ferric Binding Protein (FBP)

PDB ID 1xc1

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