2v30

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[[Image:2v30.png|left|200px]]
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==Human orotidine 5'-phosphate decarboxylase domain of uridine monophospate synthetase (UMPS) in complex with its product UMP.==
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<StructureSection load='2v30' size='340' side='right' caption='[[2v30]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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{{STRUCTURE_2v30| PDB=2v30 | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2v30]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V30 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V30 FirstGlance]. <br>
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===HUMAN OROTIDINE 5'-PHOSPHATE DECARBOXYLASE DOMAIN OF URIDINE MONOPHOSPATE SYNTHETASE (UMPS) IN COMPLEX WITH ITS PRODUCT UMP.===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=U5P:URIDINE-5-MONOPHOSPHATE'>U5P</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jgy|2jgy]]</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] </span></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v30 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v30 OCA], [http://pdbe.org/2v30 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2v30 RCSB], [http://www.ebi.ac.uk/pdbsum/2v30 PDBsum]</span></td></tr>
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[[2v30]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V30 OCA].
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</table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v3/2v30_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2v30 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Uridine 5'-monophosphate synthase|Uridine 5'-monophosphate synthase]]
*[[Uridine 5'-monophosphate synthase|Uridine 5'-monophosphate synthase]]
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[[Category: Homo sapiens]]
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__TOC__
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</StructureSection>
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[[Category: Human]]
[[Category: Orotidine-5'-phosphate decarboxylase]]
[[Category: Orotidine-5'-phosphate decarboxylase]]
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[[Category: Arrowsmith, C.]]
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[[Category: Arrowsmith, C]]
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[[Category: Berglund, H.]]
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[[Category: Berglund, H]]
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[[Category: Busam, R.]]
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[[Category: Busam, R]]
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[[Category: Collins, R.]]
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[[Category: Collins, R]]
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[[Category: Dahlgren, L G.]]
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[[Category: Dahlgren, L G]]
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[[Category: Edwards, A.]]
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[[Category: Edwards, A]]
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[[Category: Flodin, S.]]
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[[Category: Flodin, S]]
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[[Category: Flores, A.]]
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[[Category: Flores, A]]
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[[Category: Graslund, S.]]
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[[Category: Graslund, S]]
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[[Category: Hallberg, B M.]]
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[[Category: Hallberg, B M]]
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[[Category: Hammarstrom, M.]]
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[[Category: Hammarstrom, M]]
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[[Category: Holmberg-Schiavone, L.]]
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[[Category: Holmberg-Schiavone, L]]
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[[Category: Johansson, I.]]
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[[Category: Johansson, I]]
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[[Category: Kallas, A.]]
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[[Category: Kallas, A]]
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[[Category: Karlberg, T.]]
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[[Category: Karlberg, T]]
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[[Category: Kotenyova, T.]]
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[[Category: Kotenyova, T]]
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[[Category: Lehtio, L.]]
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[[Category: Lehtio, L]]
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[[Category: Moche, M.]]
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[[Category: Moche, M]]
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[[Category: Nordlund, P.]]
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[[Category: Nordlund, P]]
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[[Category: Nyman, T.]]
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[[Category: Nyman, T]]
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[[Category: Ogg, D.]]
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[[Category: Ogg, D]]
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[[Category: Persson, C.]]
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[[Category: Persson, C]]
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[[Category: Sagemark, J.]]
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[[Category: Structural genomic]]
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[[Category: Sgc, Structural Genomics Consortium.]]
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[[Category: Sagemark, J]]
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[[Category: Stenmark, P.]]
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[[Category: Stenmark, P]]
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[[Category: Sundstrom, M.]]
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[[Category: Sundstrom, M]]
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[[Category: Thorsell, A G.]]
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[[Category: Thorsell, A G]]
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[[Category: Van-Den-Berg, S.]]
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[[Category: Weigelt, J]]
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[[Category: Weigelt, J.]]
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[[Category: Welin, M]]
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[[Category: Welin, M.]]
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[[Category: Berg, S van der]]
[[Category: Decarboxylase]]
[[Category: Decarboxylase]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]

Current revision

Human orotidine 5'-phosphate decarboxylase domain of uridine monophospate synthetase (UMPS) in complex with its product UMP.

2v30, resolution 2.00Å

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OCA

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