2qt5

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[[Image:2qt5.png|left|200px]]
 
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{{STRUCTURE_2qt5| PDB=2qt5 | SCENE= }}
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==Crystal Structure of GRIP1 PDZ12 in Complex with the Fras1 Peptide==
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<StructureSection load='2qt5' size='340' side='right'caption='[[2qt5]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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===Crystal Structure of GRIP1 PDZ12 in Complex with the Fras1 Peptide===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2qt5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QT5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QT5 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_18155042}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qt5 OCA], [https://pdbe.org/2qt5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qt5 RCSB], [https://www.ebi.ac.uk/pdbsum/2qt5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qt5 ProSAT]</span></td></tr>
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[[2qt5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QT5 OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/GRIP1_RAT GRIP1_RAT] May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.<ref>PMID:9069286</ref>
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<ref group="xtra">PMID:018155042</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qt/2qt5_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qt5 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Feng, W.]]
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[[Category: Feng W]]
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[[Category: Long, J.]]
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[[Category: Long J]]
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[[Category: Wei, Z.]]
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[[Category: Wei Z]]
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[[Category: Zhang, M.]]
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[[Category: Zhang M]]
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[[Category: Zhao, Y.]]
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[[Category: Zhao Y]]
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[[Category: Cell junction]]
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[[Category: Endoplasmic reticulum]]
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[[Category: Membrane]]
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[[Category: Pdz tandem]]
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[[Category: Pdz-peptide complex]]
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[[Category: Peptide binding protein]]
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[[Category: Postsynaptic cell membrane]]
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[[Category: Protein binding]]
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[[Category: Synapse]]
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Current revision

Crystal Structure of GRIP1 PDZ12 in Complex with the Fras1 Peptide

PDB ID 2qt5

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