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1xm8

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[[Image:1xm8.jpg|left|200px]]<br /><applet load="1xm8" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1xm8, resolution 1.74&Aring;" />
 
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'''X-RAY STRUCTURE OF GLYOXALASE II FROM ARABIDOPSIS THALIANA GENE AT2G31350'''<br />
 
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==About this Structure==
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==X-RAY STRUCTURE OF GLYOXALASE II FROM ARABIDOPSIS THALIANA GENE AT2G31350==
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1XM8 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=FE:'>FE</scene>, <scene name='pdbligand=ACY:'>ACY</scene> and <scene name='pdbligand=PEG:'>PEG</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Hydroxyacylglutathione_hydrolase Hydroxyacylglutathione hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.2.6 3.1.2.6] Known structural/functional Sites: <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+A+700'>AC1</scene>, <scene name='pdbsite=AC2:Fe+Binding+Site+For+Residue+A+701'>AC2</scene>, <scene name='pdbsite=AC3:Zn+Binding+Site+For+Residue+B+703'>AC3</scene>, <scene name='pdbsite=AC4:Fe+Binding+Site+For+Residue+B+704'>AC4</scene>, <scene name='pdbsite=AC5:Acy+Binding+Site+For+Residue+A+800'>AC5</scene>, <scene name='pdbsite=AC6:Acy+Binding+Site+For+Residue+B+801'>AC6</scene> and <scene name='pdbsite=AC7:Peg+Binding+Site+For+Residue+A+900'>AC7</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XM8 OCA].
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<StructureSection load='1xm8' size='340' side='right'caption='[[1xm8]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
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[[Category: Arabidopsis thaliana]]
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== Structural highlights ==
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[[Category: Hydroxyacylglutathione hydrolase]]
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<table><tr><td colspan='2'>[[1xm8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XM8 FirstGlance]. <br>
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[[Category: Single protein]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74&#8491;</td></tr>
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[[Category: Allard, S T.M.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Bingman, C A.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xm8 OCA], [https://pdbe.org/1xm8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xm8 RCSB], [https://www.ebi.ac.uk/pdbsum/1xm8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xm8 ProSAT], [https://www.topsan.org/Proteins/CESG/1xm8 TOPSAN]</span></td></tr>
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[[Category: Bitto, E.]]
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</table>
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[[Category: CESG, Center for Eukaryotic Structural Genomics.]]
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== Function ==
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[[Category: Jr., G N.Phillips.]]
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[https://www.uniprot.org/uniprot/GLO2N_ARATH GLO2N_ARATH] Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.<ref>PMID:16227621</ref>
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[[Category: Smith, D W.]]
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== Evolutionary Conservation ==
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[[Category: Wesenberg, G E.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: ACY]]
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Check<jmol>
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[[Category: FE]]
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<jmolCheckbox>
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[[Category: PEG]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xm/1xm8_consurf.spt"</scriptWhenChecked>
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[[Category: ZN]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: at2g31350]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: b-lactamase fold]]
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</jmolCheckbox>
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[[Category: center for eukaryotic structural genomics]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xm8 ConSurf].
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[[Category: cesg]]
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<div style="clear:both"></div>
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[[Category: metallo-hydrolase]]
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[[Category: mitochondrial isozyme]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomics]]
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[[Category: thioester hydrolase]]
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[[Category: zinc/iron binuclear center]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:56:23 2008''
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==See Also==
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*[[Glyoxalase 3D structures|Glyoxalase 3D structures]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Arabidopsis thaliana]]
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[[Category: Large Structures]]
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[[Category: Allard STM]]
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[[Category: Bingman CA]]
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[[Category: Bitto E]]
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[[Category: Phillips Jr GN]]
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[[Category: Smith DW]]
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[[Category: Wesenberg GE]]

Current revision

X-RAY STRUCTURE OF GLYOXALASE II FROM ARABIDOPSIS THALIANA GENE AT2G31350

PDB ID 1xm8

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