3ag6

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[[Image:3ag6.png|left|200px]]
 
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{{STRUCTURE_3ag6| PDB=3ag6 | SCENE= }}
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==Crystal Structure of Pantothenate Synthetase from Staphylococcus aureus in complex with pantoyl adenylate==
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<StructureSection load='3ag6' size='340' side='right'caption='[[3ag6]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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===Crystal Structure of Pantothenate Synthetase from Staphylococcus aureus in complex with pantoyl adenylate===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3ag6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_NCTC_8325 Staphylococcus aureus subsp. aureus NCTC 8325]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AG6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AG6 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_20568730}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=PAJ:PANTOYL+ADENYLATE'>PAJ</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ag6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ag6 OCA], [https://pdbe.org/3ag6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ag6 RCSB], [https://www.ebi.ac.uk/pdbsum/3ag6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ag6 ProSAT]</span></td></tr>
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[[3ag6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AG6 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PANC_STAA8 PANC_STAA8] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ag/3ag6_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ag6 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Pantothenate synthetase|Pantothenate synthetase]]
*[[Pantothenate synthetase|Pantothenate synthetase]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:020568730</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Pantoate--beta-alanine ligase]]
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[[Category: Staphylococcus aureus subsp. aureus NCTC 8325]]
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[[Category: Staphylococcus aureus]]
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[[Category: Inoue T]]
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[[Category: Inoue, T.]]
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[[Category: Konishi S]]
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[[Category: Konishi, S.]]
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[[Category: Matsumura H]]
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[[Category: Matsumura, H.]]
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[[Category: Satoh A]]
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[[Category: Satoh, A.]]
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[[Category: Smith AG]]
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[[Category: Smith, A G.]]
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[[Category: Stickland HG]]
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[[Category: Stickland, H G.]]
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[[Category: Tamura H]]
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[[Category: Tamura, H.]]
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[[Category: Whitney HM]]
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[[Category: Whitney, H M.]]
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[[Category: Atp-binding]]
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[[Category: Atp-dependent enzyme]]
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[[Category: Ligase]]
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[[Category: Nucleotide-binding]]
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[[Category: Pantothenate biosynthesis]]
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[[Category: Pantothenate synthetase]]
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Current revision

Crystal Structure of Pantothenate Synthetase from Staphylococcus aureus in complex with pantoyl adenylate

PDB ID 3ag6

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